Carrier protein
|
WikiDoc Resources for Carrier protein |
|
Articles |
|---|
|
Most recent articles on Carrier protein Most cited articles on Carrier protein |
|
Media |
|
Powerpoint slides on Carrier protein |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Carrier protein at Clinical Trials.gov Trial results on Carrier protein Clinical Trials on Carrier protein at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Carrier protein NICE Guidance on Carrier protein
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Carrier protein Discussion groups on Carrier protein Patient Handouts on Carrier protein Directions to Hospitals Treating Carrier protein Risk calculators and risk factors for Carrier protein
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Carrier protein |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Overview
Carrier proteins are proteins that transport a specific substance or group of substances across intracellular compartments or in extracellular fluids (e.g. in the blood) or else across the cell membrane. Some of the carriers are water-soluble proteins that may or may not interact with biological membranes, such as some transporters of small hydrophobic molecules, whereas others are integral transmembrane proteins.
Carrier proteins of the cell membrane transport substances down their concentration gradient out of or into the cell by facilitated diffusion and active transport. Each carrier protein is designed to recognize only one substance or one group of very similar substances. The molecule or ion to be transported (the substrate) must first bind at a binding site at the carrier molecule, with a certain binding affinity. Following binding, and while the binding site is facing, say, outwards, the carrier will capture or occlude (take in and retain) the substrate within its molecular structure and cause an internal translocation, so that it now faces the other side of the membrane. The substrate is finally released at that site, according to its binding affinity there. All steps are reversible.
For example:
- Diffusion of sugars, amino acids,nucleoside.
- Uptake of glucose.
See also
External links
- Carrier+proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
 | This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |