17 alpha-hydroxylase deficiency surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Overview

Affected 46,XY patients require gonadectomy to prevent malignant degeneration of testes. Reconstructive surgery for ambiguous genitalia in genetically male patients may be advised.

Surgery

References

  1. Lee PA, Houk CP, Ahmed SF, Hughes IA (2006). "Consensus statement on management of intersex disorders. International Consensus Conference on Intersex". Pediatrics. 118 (2): e488–500. doi:10.1542/peds.2006-0738. PMID 16882788.
  2. Looijenga LH, Hersmus R, Oosterhuis JW, Cools M, Drop SL, Wolffenbuttel KP (2007). "Tumor risk in disorders of sex development (DSD)". Best Pract. Res. Clin. Endocrinol. Metab. 21 (3): 480–95. doi:10.1016/j.beem.2007.05.001. PMID 17875493.