Family history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and Keywords: FH
Overview
In medicine, a family history consists of information about disorders that a patient's direct blood relatives have suffered from. Genealogy typically includes very little of the medical history of the family, but the medical history could be considered a specific subset of the total history of a family.
Definition
A family history of coronary artery disease is defined as the presence of coronary artery disease in a first degree relative < 60 years of age.
Uses
Although often neglected,[1] many doctors glean information on family morbidity of particular diseases (e.g. cardiovascular diseases, autoimmune disorders, mental disorders, diabetes, cancer) to appreciate whether a person is at risk for developing similar problems. Use of a genogram can be helpful in a family history, which is in the format of a family tree.
Family histories may be imprecise because of various possible reasons:
- Adoption or illegitimacy
- Lack of contact between close relatives
- Uncertainty about the relative's exact diagnosis
In complex situations, a family tree may be necessary to cover the necessary aspects.
Consequences
Not all positive family histories imply a genetic cause. If various members of the same family have been exposed to the same toxin, then they may develop similar symptoms without a genetic cause.
If a patient has a strong family history of a particular disorder (or group of disorders), this will generally lead to a lower threshold for investigating symptoms.
In diseases with a known hereditary component, many healthy people are now tested early to prevent the symptoms from developing. This has become accepted in cystic fibrosis, hemochromatosis and various other disorders.
References
- ↑ Rich EC, Burke W, Heaton CJ, Haga S, Pinsky L, Short MP, Acheson L. Reconsidering the family history in primary care. J Gen Intern Med 2004;19:273-80. PMID 15009784.