Foster Kennedy syndrome
Foster Kennedy syndrome | |
Classification and external resources | |
ICD-9 | 377.04 |
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DiseasesDB | 31967 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Gowers-Paton-Kennedy syndrome, Kennedy's phenomenon or Kennedy's syndrome
Overview
Foster Kennedy syndrome refers to a constellation of findings associated with brain tumors involving the frontal lobe.[1]
Historical Perspective
The syndrome was first extensively noted by Robert Foster Kennedy in 1911, a British neurologist, who spent most of his career working in the United States of America.[2] However, the first mention of the syndrome came from a William Gowers in 1893. Schultz-Zehden described the symptoms again in 1905. A later description was written by Wilhelm Uhthoff in 1915.[3]
Although "Foster Kennedy syndrome" is equated with "Kennedy syndrome",[4] it should not be confused with Kennedy disease, which is named for W. R. Kennedy.
Pseudo-Foster Kennedy syndrome is defined as one-sided optic atrophy with papilledema in the other eye but with the absence of a mass.[5]
Diagnosis
Physical Examination
Neurologic
- Optic atrophy in the ipsilateral eye
- Papilledema in the contralateral eye
- Central scotoma (loss of vision in the middle of the visual fields) in the ipsilateral eye
- anosmia (loss of smell) ipsilaterally
This syndrome is due to optic nerve compression, olfactory nerve compression, and increased intracranial pressure (ICP) secondary to a mass (such as meningioma or plasmacytoma, usually an olfactory groove meningioma).[6][7] There are other symptoms present in some cases such as nausea and vomiting, memory loss and emotional lability (i.e. frontal lobe signs).[7]
Treatment and prognosis
The treatment, and therefore prognosis, varies depending upon the underlying tumour.[7]
References
- ↑ Template:DorlandsDict
- ↑ Thorofare, NJ (1911). Kennedy F; Retrobulbar neuritis as an exact diagnostic sign of certain tumors and abscesses in the frontal lobe. American Journal of the Medical Sciences.
- ↑ "Kennedy's syndrome". Retrieved 2008-08-13.
- ↑ Template:DorlandsDict
- ↑ Bansal S, Dabbs T, Long V (2008). "Pseudo-Foster Kennedy Syndrome due to unilateral optic nerve hypoplasia: a case report". J Med Case Reports. 2: 86. doi:10.1186/1752-1947-2-86. PMC 2278154. PMID 18348732. Retrieved 2008-08-13.
- ↑ Longmore, Murray (2007). Oxford Handbook of Clinicial Medicine, 7th edition. Oxford University Press. p. 690. ISBN 0-19-856837-1. Unknown parameter
|coauthors=
ignored (help) - ↑ 7.0 7.1 7.2 Willacy, Hayley. "Foster Kennedy syndrome". Retrieved 2008-08-13.