High endothelial venules
(Redirected from High endothelial venule)
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
High endothelial venules, or HEVs, are a subtype of blood endothelium present within lymph nodes; used by various leukocytes to gain entry into the lymph node via the blood.[1]
The HEVs are made up of cuboidal endothelial cells, with various receptors to allow entry/rolling interactions between leukocytes and the endothelium.
High endothelial venules are found in lymph nodes and tonsils and Peyer's patches, but not in the thymus or spleen.[2]