Hypoplasia
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Overview
Hypoplasia is an incomplete or arrested development of an organ or a part [1]. It is descriptive of many medical conditions such as:
- Underdeveloped breasts during puberty.
- Underdeveloped testes in Klinefelter's syndrome.
- Underdeveloped thymus in DiGeorge syndrome.
- Underdeveloped labia majora in popliteal pterygium syndrome.
- Underdeveloped cerebellum caused by mutation in the Reelin gene.
- Underdeveloped tooth caused by oral pathology, such as Turner's hypoplasia.
- Underdeveloped chambers of the heart in hypoplastic left heart syndrome and hypoplastic right heart syndrome
- Underdeveloped optic nerve in optic nerve hypoplasia
- Underdeveloped sacrum in sacral agenesis
- Underdeveloped facial muscle in asymmetric crying facies