IMPROVEDD VTE risk score

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Seyedmahdi Pahlavani, M.D. [3], Anmol Pitliya, M.B.B.S. M.D.[4]

Synonyms and keywords:

Overview

The IMPROVEDD VTE Risk Score, which incorporates D-dimer measurement into the IMPROVE (International Medical Prevention Registry on Venous Thromboembolism) score, refines the prediction of symptomatic venous thromboembolism (including symptomatic deep-vein thrombosis, nonfatal pulmonary embolism, and death related to venous thromboembolism) events in acutely ill hospitalized patients up to 77 days of hospitalization.

IMPROVEDD VTE Risk Score

The IMPROVEDD VTE Risk Score, which incorporates D-dimer measurement into the IMPROVE (International Medical Prevention Registry on Venous Thromboembolism) score, refines the prediction of symptomatic venous thromboembolism (including symptomatic deep-vein thrombosis, nonfatal pulmonary embolism, and death related to venous thromboembolism) events in acutely ill hospitalized patients up to 77 days of hospitalization.^[1]^[2]

IMPROVEDD VTE Risk Score Calculator

Shown below is the calculator for IMPROVEDD Score for VTE (check all the boxes that apply):

Interpretation

Score = 0: Predicted Risk of Symptomatic VTE is 0.4% at 35-42 days and 0.5% at 77 days
Score = 1: Predicted Risk of Symptomatic VTE is 0.6% at 35-42 days and 0.7% at 77 days
Score = 2: Predicted Risk of Symptomatic VTE is 0.8% at 35-42 days and 1.0% at 77 days
Score = 3: Predicted Risk of Symptomatic VTE is 1.2% at 35-42 days and 1.4% at 77 days
Score = 4: Predicted Risk of Symptomatic VTE is 1.6% at 35-42 days and 1.9% at 77 days
Score ≥ 5: Predicted Risk of Symptomatic VTE is 2.2% at 35-42 days and 2.7% at 77 days

References

↑ Gibson CM, Spyropoulos AC, Cohen AT, Hull RD, Goldhaber SZ, Yusen RD, Hernandez AF, Korjian S, Daaboul Y, Gold A, Harrington RA, Chi G. (2017). "The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification". TH Open. 01 (01): e56–e65. doi:10.1055/s-0037-1603929.
↑ Spyropoulos AC, Anderson FA, Fitzgerald G, Decousus H, Pini M, Chong BH; et al. (2011). "Predictive and associative models to identify hospitalized medical patients at risk for VTE". Chest. 140 (3): 706–14. doi:10.1378/chest.10-1944. PMID 21436241.

[1] Gibson CM, Spyropoulos AC, Cohen AT, Hull RD, Goldhaber SZ, Yusen RD, Hernandez AF, Korjian S, Daaboul Y, Gold A, Harrington RA, Chi G. (2017). "The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification". TH Open. 01 (01): e56–e65. doi:10.1055/s-0037-1603929.

[pmid21436241-2] Spyropoulos AC, Anderson FA, Fitzgerald G, Decousus H, Pini M, Chong BH; et al. (2011). "Predictive and associative models to identify hospitalized medical patients at risk for VTE". Chest. 140 (3): 706–14. doi:10.1378/chest.10-1944. PMID 21436241.

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IMPROVEDD VTE Risk Score Calculator
Variable	Score
Prior episode of VTE	3
Thrombophilia	2
Paralysis of the lower extremity during the hospitalization	2
Current malignancy	2
Immobilization for at least 7 days	1
ICU or CCU admission	1
Age more than 60 years	1
D-dimer ≥2× upper limit of normal (or ≥1.0 μg/mL)	2
IMPROVEDD Score:
Predicted Risk of Symptomatic VTE: