Ischemic colitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]

Overview

There are no specific blood tests for ischemic colitis, but an elevated white blood cell count may be present. Other laboratory findings in ischemic colitis include electrolyte and renal abnormalities secondary to dehydration, metabolic acidosis, and lactate level may be elevated due to any tissue hypoxia.

Laboratory Findings

The laboratory findings for ischemic colitis are as follows:

• Mild leukocytosis with a left shift
• Electrolyte and renal abnormalities secondary to dehydration
• Metabolic acidosis may be present
• Lactate level may be elevated due to any tissue hypoxia
  • Sensitivity of 82% and a specificity of 87% in predicting early colonic ischemia.
• The sensitivity of tests among 73 patients were:
  • Elevated white blood cell count more than 15,000/mm³ in 20 patients (27%)
  • The serum bicarbonate level was less than 24 mmol/L in 26 patients (36%)