Anhidrosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Hypohidrosis; oligidria; oligohidrosis; sweating deficiency

Overview

Anhidrosis means lack of sweating.

Causes

It may be caused by underactivity of the sympathetic nervous system. Eccrine sweat glands are innervated by muscarinic acetylcholine receptors. Therefore, antimuscarinic drugs can cause anhidrosis.

Common Causes

• Miscellaneous conditions
  • Ross syndrome
• Symptoms and signs
  • Horner syndrome
  • Chromosomal abnormalities
  • Chromosome 22q13.3 deletion syndrome

• Autosomal dominant conditions
  • Dermatopathia pigmentosa reticularis
  • Hay-Wells syndrome
  • Hereditary sensory and autonomic neuropathy type 1E
  • Hypohidrotic ectodermal dysplasia, autosomal dominant
  • Limb-mammary syndrome
  • Marshall syndrome
  • Naegeli-Franceschetti-Jadassohn syndrome
  • Rapp-Hodgkin ectodermal dysplasia syndrome

• Autosomal recessive conditions
  • Hereditary sensory and autonomic neuropathy type 4
  • Hypohidrotic ectodermal dysplasia, autosomal recessive type
  • Rosselli-Gulienetti syndrome

• X-linked inherited conditions
  • Bazex-Dupre-Christol syndrome
  • Hypohidrotic ectodermal dysplasia with immune deficiency
  • Hypohidrotic ectodermal dysplasia, X-linked

• Bacteria and bacterial conditions
  • Lepromatous leprosy
  • Tuberculoid leprosy

• Iatrogenic conditions
  • Sympathectomy
  • Drugs, hormones and mediators
  • Hexamethonium
  • Topiramate
  • Zonisamide

• Drug Causes

• • Benztropine Mesylate
  • Propantheline bromide

Related Chapters

• Horner's syndrome
• Hyperhidrosis (excessive sweating)

References

de:Anhidrose

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