Thiethylperazine

Thiethylperazine

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	R06AD03 (WHO)
Pharmacokinetic data
Protein binding	60%
Identifiers
IUPAC name 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
CAS Number	1420-55-9 Y
PubChem CID	5440
DrugBank	DB00372 Y
ChemSpider	5245 Y
UNII	8ETK1WAF6R
KEGG	D02354 Y
ChEBI	CHEBI:9544 Y
ChEMBL	ChEMBL1378 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H29N3S2
Molar mass	399.618 g/mol
3D model (JSmol)	Interactive image
SMILES S(c2cc1N(c3c(Sc1cc2)cccc3)CCCN4CCN(C)CC4)CC
InChI InChI=1S/C22H29N3S2/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24/h4-5,7-10,17H,3,6,11-16H2,1-2H3 Y Key:XCTYLCDETUVOIP-UHFFFAOYSA-N Y
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Clinical Trials
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Definitions
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Experimental / Informatics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.

Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice.