View source for List of chemotherapeutic agents

__NOTOC__
{{SI}}
{{Seealso|Chemotherapy regimens}}
{{CMG}}; {{AE}} {{AV}} {{AP}}

==Overview==
This is a '''list of chemotherapeutic agents''' (also known as '''cytotoxic agents''') that are known to be of use in [[chemotherapy]] for [[cancer]].  This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into [[chemotherapy regimens]] for polychemotherapy (combination chemotherapy). For example, the [[CHOP]] regimen consists of [[cyclophosphamide]], [[hydroxydaunorubicin]] (doxorubicin), [[vincristine]] (Oncovin), and prednisone. 

Besides chemotherapy, medical oncology ([[pharmacotherapy]] for cancer) includes several noncytotoxic classes of therapy, such as [[hormonal therapy (oncology)|hormonal therapy]] and [[targeted therapy]] (biologic therapy). Those agents are described in the relevant articles. 

==Chemotherapeutic Agents by Category==
===Cytotoxic Chemotherapy===
===== Alkylating agents =====
*[[Estramustine]]

===== Anthracyclines =====
*[[Idarubicin hydrochloride|Idarubicin (Idamycin)]]

===== Antimetabolites =====
*[[Fluorouracil |Fluorouracil (Adrucil, Efudex)]]

===== Antimitotic agent=====
*[[Dexrazoxane]]

===== DNA synthesis inhibitors =====
*[[Streptozocin|Streptozocin (Zanosar)]]

===== Microtubule inhibitors =====
*[[Ixabepilone|Ixabepilone (Ixempra)]]

===== Nitrogen mustards =====
===== Nitrosureas =====
===== Platinum agents =====
===== Proteasome inhibitors =====
===== Taxanes =====
===== Topoisomerase inhibitors =====
*[[Irinotecan hydrochloride|Irinotecan (Camptosar)]]

===== Vinca alkaloids =====
----

=== Kinase inhibitors ===
*[[Idelalisib|Idelalisib (Zydelig)]]
*[[Palbociclib|Palbociclib (Ibrance)]]

=== HDAC inhibitors ===
----
=== Endocrine therapy ===
===== Antiandrogens =====
===== Steroid synthesis inhibitors =====
===== Androgen receptor inhibitors =====
*[[Nilutamide|Nilutamide (Nilandron)]]

===== 5α-reductase inhibitors =====
===== GnRH agonists =====
* [[Buserelin|Buserelin (Superfact)]]

===== GnRH antagonists =====
*[[Degarelix]]

===== Aromatase inhibitors =====
===== Selective estrogen receptor modulators =====
----
=== Biologics ===
===== Antibody medications =====
*[[Ibritumomab tiuxetan]]
*[[Nivolumab |Nivolumab (Opdivo)]]
*[[Pembrolizumab|Pembrolizumab (KEYTRUDA)]]

===== Antibody-drug conjugates =====
===== Anti-HER2 medications =====
===== IL-6 inhibitors =====
*[[Siltuximab|Siltuximab (Sylvant)]]

===== IL-2 inhibitors =====
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]

===== Enzyme Inhibitors =====
*[[Belinostat|Belinostat (Beleodaq)]]

===== Immunotherapy =====
===== Immunomodulatory drugs (IMiDs) =====
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
----

=== Hematopoietic Growth Factors ===
===== Erythrocyte growth factors =====
===== Granulocyte growth factors =====
*[[Filgrastim|Filgrastim (Granix)]]
*[[Sargramostim|Sargramostin (Leukine)]]

===== Megakaryocyte growth factors =====
----
=== Supportive Medications ===
===== Chemotherapy protective agents =====
*[[Amifostine|Amifostine (Ethyol)]]
*[[Cyanocobalamin|Cyanocobalamin]]
*[[Dexrazoxane|Dexrazoxane (Zinecard)]]
*[[Folinic acid|Folinic acid (Leucovorin)]]
*[[Glucarpidase|Glucarpidase (Voraxaze)]]
*[[Levoleucovorin|Levoleucovorin (Fusilev)]]
*[[Mesna|Mesna (Mesnex)]]



===== Antiemetic agents =====
*[[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]

===== RANK ligand inhibitors =====
----
=== Miscellaneous ===
*[[Pegaspargase|Pegaspargase (Oncaspar)]]
*[[Ramucirumab|Ramucirumab (Cyramza)]]
----

== Chemotherapeutic Agents in Alphabetical Order ==
* [[Abiraterone|Abiraterone acetate (Zytiga)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Asparaginase Erwinia chrysanthemi|Asparaginase Erwinia chrysanthemi (Erwinaze)]]
* [[Axitinib|Axitinib (Inlyta)]]
* [[Azacytidine|Azacytidine (Vidaza)]]
* [[Belinostat|Belinostat (Beleodaq)]]
* [[Bendamustine|Bendamustine (Treanda)]]
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
* [[Buserelin|Buserelin (Suprefact)]]
* [[Busulfan|Busulfan (Myleran-oral)]]
* [[Cabazitaxel|Cabazitaxel (Jevtana)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Carboplatin|Carboplatin (Paraplatin)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Daunorubicin|Daunorubicin (Daunoxome)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Degarelix|Degarelix (Firmagon)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Denosumab|Denosumab (Xgeva)]]
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Eribulin mesylate|Eribulin (Halaven)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Etoposide|Etoposide (Vespid)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Filgrastim|Filgrastim (Neupogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fludarabine|Fludarabine (Fludara)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Goserelin acetate|Goserelin Acetate (Zoladex)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idarubicin|Idarubicin (Idamycin)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[interferon alfa-2b|interferon alfa-2b (Intron A)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Isotretinoin|Isotretinoin (Accutane)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Letrozole|Letrozole (Femara)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Mercaptopurine|Mercaptopurine (Purinethol)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitotane|Mitotane (Lysodren)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Nelarabine|Nelarabine (Arranon)]]
* [[Netupitant and palonosetron|Netupitant and palonosetron (Akynzeo)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
* [[Nivolumab|Nivolumab (Opdivo)]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Octreotide|Octreotide (Octreotide)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pegaspargase|PEG-Asparaginase (Oncaspar)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Rituximab|Rituximab (Rituxan)]]
* [[Romidepsin|Romidepsin (Istodax)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sargramostim|Sargramostim (Leukine, Leukomax)]]
* [[Siltuximab|Siltuximab (Sylvant)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Streptozocin|Streptozocin (Zanosar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
* [[Temozolomide|Temozolomide (Temodar)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
* [[Thiotepa|Thiotepa (TESPA)]]
* [[Tocilizumab|Tocilizumab (Actemra)]]
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposomal|Vincristine liposomal (Marqibo)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Zoledronic acid|Zoledronic Acid (Zometa)]]

[[Category:Chemotherapeutic agents| ]]