View source for Febrile neutropenia risk factors

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{{For|patient information page|Febrile neutropenia (patient information)}}
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{{SK}} F and N; fever and neutropenia; FN; hot and low; hot leuk; neutropenic fever; neutropenic fever syndrome; neutropenic sepsis

== Overview ==
Patients with an anticipated duration of neutropenia longer than 10 days, patients undergoing intensive induction/consolidation therapy for acute leukemias, patients receiving treatment with alemtuzumab-containing regimens, allogeneic HSCT recipients, and those with GVHD following allogeneic HSCT are categorized as high risk for infectious complications.

== Risk Factors ==
{{Seealso|Antimicrobial Prophylaxis for Cancer-Related Infections}}

=== NCCN Overall Infection Risk Categories ===
The National Comprehensive Cancer Network (NCCN) devised a set of overall infection risk categories (low, intermediate, and high) in patients with cancer based on factors such as the underlying malignancy, disease status (eg, active disease, disease in remission), duration of neutropenia, prior exposure to chemotherapy, and intensity of immunosuppressive therapies.<ref>{{Cite web | title =  Prevention and Treatment of Cancer-Related Infections | accessdate =  | url = http://www.nccn.org/professionals/physician_gls/PDF/infections.pdf }}</ref>

==== Low risk for infectious complications ====
Patients with solid tumors undergoing standard chemotherapy regimens and who have an anticipated duration of neutropenia less than 7 days are considered at low risk for infectious complications.

==== Intermediate risk for infectious complications ====
Intermediate risk refer to patients with an anticipated duration of neutropenia of 7 to 10 days. Patients with lymphoma, multiple myeloma, or CLL; autologous HSCT recipients; or patients receiving treatment with purine analogue-containing regimens are also considered intermediate risk.

==== High risk for infectious complications ====
Patients with an anticipated duration of neutropenia longer than 10 days, patients undergoing intensive induction/consolidation therapy for acute leukemias, patients receiving treatment with alemtuzumab-containing regimens, allogeneic HSCT recipients, and those with GVHD following allogeneic HSCT are categorized as high risk for infectious complications.

== References ==
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[[Category:Emergency medicine]]
[[Category:Infectious disease]]
[[Category:Primary care]]
[[Category:Signs and symptoms]]
[[Category:Symptoms]]