View source for Aluminium chloride

{{DrugProjectFormSinglePage
|authorTag={{Ammu}}
|genericName=Aluminium chloride
|aOrAn=a
|drugClass=chemical
|indicationType=treatment
|indication=indicated for the control of minor [[hemorrhage]] during dental restorative procedures
|adverseReactions=[[hypersensitivity]]
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>

* Content

<!--Adult Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=* Indicated for the control of minor [[hemorrhage]] during dental restorative procedures.
* Dispense a small amount of Hemoban into a clean dappen dish or disposable cup.
* For hemorrhage control prior to making a restorative impression, soak a suitable length of retraction cord in Hemoban, then using a cord-packing instrument, place the retraction cord into the gingival sulcus. Hemoban is compatible with all impression techniques – though it is recommended that critical areas be gently rinsed with water prior to application of addition-type (VPS) impression materials to preclude inhibition of the setting reaction of the impression material.
* For minor hemorrhage control in situations other than making restorative impressions, soak a cotton pellet in Hemoban and apply for several seconds to the area, then rinse gently with water.
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Pediatric Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed=There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.

<!--Off-Label Use and Dosage (Pediatric)-->

<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Contraindications-->
|contraindications=* This product should not be used with individuals with known sensitivities to aluminum chloride.
|warnings=* Do not swallow. Keep out of reach of children. For professional dental use only.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.

<!--Administration and Monitoring-->
|administration=* Topical
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.

<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.

<!--Overdosage-->
|overdose=There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.

<!--Pharmacology-->

<!--Drug box 2-->
|drugBox={{chembox2
| Watchedfields = changed
| verifiedrevid = 477245740
| Name =
| ImageFile1 = Aluminium-trichloride-hexahydrate-white-and-yellow.jpg
<!-- | ImageSize = 150px -->
| ImageName1 = Aluminium chloride
| ImageFile2 =
| ImageName2 = Aluminium(III) Chloride
| ImageFile3 = Aluminium-trichloride-dimer-3D-balls.png
<!-- | ImageSize1 = 150px  -->
| ImageName3 = Aluminium trichloride dimer
| IUPACName = aluminium chloride
| OtherNames = aluminium(III) chloride
| Section1 = {{Chembox Identifiers
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = LIF1N9568Y
| InChI = 1/Al.3ClH/h;3*1H/q+3;;;/p-3
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 30114
| SMILES = Cl[Al](Cl)Cl
| InChIKey = VSCWAEJMTAWNJL-DFZHHIFOAR
| SMILES1 = [Al](Cl)(Cl)Cl
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/Al.3ClH/h;3*1H/q+3;;;/p-3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VSCWAEJMTAWNJL-UHFFFAOYSA-K
| CASNo = 7446-70-0
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo_Comment = (anhydrous)
| CASNo1 = 10124-27-3
| CASNo1_Comment = (hydrate)
| CASNo2 = 7784-13-6
| CASNo2_Comment = (hexahydrate)
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID=22445
| PubChem = 24012
| RTECS = BD0530000
| ATCCode_prefix = D10
| ATCCode_suffix = AX01
 }}
| Section2 = {{Chembox Properties
| Formula = AlCl<sub>3</sub>
| MolarMass = 133.34 g/mol (anhydrous)<br />241.43 g/mol (hexahydrate)
| Appearance = white or pale yellow solid,<br />[[hygroscopic]]
| Density = 2.48 g/cm<sup>3</sup> (anhydrous)<br> 1.3 g/cm<sup>3</sup> (hexahydrate)
| Solubility = 43.9 g/100 ml (0 °C)<br />44.9 g/100 ml (10 °C)<br />45.8 g/100 ml (20 °C)<br />46.6 g/100 ml (30 °C)<br />47.3 g/100 ml (40 °C)<br />48.1 g/100 ml (60 °C)<br />48.6 g/100 ml (80 °C)<br />49 g/100 ml (100 °C)
| SolubleOther = soluble in hydrogen chloride, ethanol, chloroform, carbon tetrachloride <br> slightly soluble in benzene
| MeltingPtC = 192.4
| Melting_notes = <br> (anhydrous)<br> {{convert|100|C|F K}}<br> (hexahydrate)<br> {{convert|180|C|F K}}<br> (sublimes)
| BoilingPtC = 120
| Boiling_notes = (hexahydrate)
| pKa =
| Viscosity = 0.35 cP (197 °C)<br> 0.26 cP (237 °C)<ref name=chemister>http://chemister.ru/Database/properties-en.php?dbid=1&id=353</ref>
| VaporPressure = 133.3 Pa (99 °C)<br> 13.3 kPa (151 °C)<ref name=chemister />
 }}
| Section3 = {{Chembox Structure
| MolShape = Trigonal planar<br />([[monomer]]ic vapour)
| Coordination = Octahedral (solid)<br />Tetrahedral (liquid)
| CrystalStruct = [[Monoclinic]], [[Pearson symbol|mS16]]
| SpaceGroup = C12/m1, No. 12
 }}
| Section4 = {{Chembox Thermochemistry
|   DeltaHf = −704.2 kJ/mol<ref name=chemister /><ref name = zumdahl>{{cite book| author = Zumdahl, Steven S.|title =Chemical Principles 6th Ed.| publisher = Houghton Mifflin Company| year = 2009| isbn = 0-618-94690-X}}</ref>
|   Entropy = 111 J/mol·K<ref name = zumdahl/>
|   DeltaGf = -628.6 kJ/mol<ref name=chemister />
|   HeatCapacity = 91 J/mol·K<ref name=chemister />
}}
| Section7 = {{Chembox Hazards
| GHSPictograms = {{GHS05}}<ref name="sigma">{{Sigma-Aldrich|id=563919|name=Aluminum chloride|accessdate=2014-05-05}}</ref>
| GHSSignalWord = Danger
| HPhrases = {{H-phrases|314}}<ref name="sigma" />
| PPhrases = {{P-phrases|280|310|305+351+338}}<ref name="sigma" />
| NFPA-H = 3
| NFPA-F = 0
| NFPA-R = 2
| EUClass = {{Hazchem C}}
| RPhrases = {{R34}}
| SPhrases = {{S1/2}}, {{S7/8}}, {{S28}}, {{S45}}
| LD50 = ''anhydrous:'' <br> 380 mg/kg, rat (oral) <hr> ''hexahydrate:'' <br> 3311 mg/kg, rat (oral)
}}
| Section8 = {{Chembox Related
| OtherAnions = [[Aluminium fluoride]]<br />[[Aluminium bromide]]<br />[[Aluminium iodide]]
| OtherCations = [[Boron trichloride]]<br />[[Gallium trichloride]]<br />[[Indium(III) chloride]]<br />[[Magnesium chloride]]
| Function = [[Lewis acid]]s
| OtherFunctn = [[Iron(III) chloride]]<br />[[Boron trifluoride]]
 }}
}}
|mechAction=* Hemoban is formulated to control minor hemorrhage during dental restorative procedures. Hemoban may be used on a cotton pellet or more commonly with retraction cord. Hemoban contains 25% aluminum chloride.



<!--Structure-->
|structure=<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.

<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.

<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.

<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.

<!--How Supplied-->
|storage=* Store between 59°-86°F (15°-30°C). Protect from freezing.
|packLabel=<!--Patient Counseling Information-->
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.

<!--Precautions with Alcohol-->
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

<!--Brand Names-->
|brandNames=*HEMOBAN ®<ref>{{Cite web | title = HEMOBAN- aluminum chloride solution | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7054c4ea-fee2-4627-aff2-e99ceb1080c7 }}</ref>

<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>

<!--Drug Shortage Status-->
|drugShortage=
}}
{{LabelImage
|fileName=Aluminium chloride.jpg
}}
{{LabelImage
|fileName=DailyMed - HEMOBAN- aluminum chloride solution  .png
}}
<!--Pill Image-->



<!--Label Display Image-->





<!--Category-->

[[Category:Drug]]

[[Category:Chlorides]]
[[Category:Metal halides]]
[[Category:Aluminium compounds]]
[[Category:Inorganic compounds]]
[[Category:Reagents for organic chemistry]]
[[Category:Deliquescent substances]]