View source for Desquamation

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'''Desquamation''' is the shedding of the [[Epidermis (skin)|outer layer]]s of the [[skin]].  The word comes from the [[Latin]] '' 'desquamare' '', meaning "to scrape the [[scale (zoology)|scales]] off a [[fish]]".

For example, once the [[rash]] of [[measles]] fades, there is desquamation. Also seen in [[Toxic Shock Syndrome]]
in the eye, the epithelial basement membrane (lens capsule) completely encloses the lens, therefore desquamation of aging cells is impossible, and due to the complete absence of blood vessels or transport of metabolites in this area, there is no subsequent remodelling of these fibres, nor removal of degraded lens fibres.

Nonpathologic desquamation occurs when corneocytes, after move apically over about 14 days, are individually shed invisibly.<ref name="pmid8460510">{{cite journal |author=Jackson SM, Williams ML, Feingold KR, Elias PM |title=Pathobiology of the stratum corneum |journal=West. J. Med. |volume=158 |issue=3 |pages=279–85 |year=1993 |month=March |pmid=8460510 |pmc=1311754 |doi= |url=}}</ref>{{rp|279}}  In pathologic desquamation, the stratum corneum becomes thicker ([[hyperkeratosis]]), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, forming visible scales.<ref name="pmid8460510" />{{rp|279}}

== References ==
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{{Skin and subcutaneous tissue symptoms and signs}}

[[Category:Animal physiology]]
[[Category:Dermatologic terminology]]
[[Category:Medical signs]]

{{Symptoms and signs}}
[[Category: Dermatology]]
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