View source for Carl Ferdinand Cori

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[[Image:Carl Ferdinand Cori.jpg|thumb|right|Carl Ferdinand Cori]]
'''Carl Ferdinand Cori''' ([[December 5]], [[1896]] &ndash; [[October 20]], [[1984]]) was an [[Austrian-American]] [[biochemistry|biochemist]] and pharmacologist born in [[Prague]] (then in [[Austria-Hungary]], now [[Czech Republic]]) who, together with his wife [[Gerty Cori]] and Argentine physiologist [[Bernardo Houssay]], received a [[Nobel Prize]] in [[1947]] for their discovery of how [[glycogen]] (animal starch) - a derivative of [[glucose]] - is broken down and resynthesized in the body, for use as a store and source of energy.  In 2004 both were designated an [[ACS National Historical Chemical Landmarks|ACS National Historical Chemical Landmark]] in recognition of their work that elucidated carbohydrate metabolism.[http://acswebcontent.acs.org/landmarks/landmarks/glucose/glucose.html]

Carl was the son of Carl Cori, a physician, and Martha Lippich, he grew up in [[Trieste]] where his father was the director of the Marine Biological Station. In late [[1914]] the Cori family moved to [[Prague]] and Carl entered the medical school of the [[German Charles-Ferdinand University in Prague]]. While studying there he met [[Gerty Cori|Gerty Theresa Radnitz]]. He was drafted into the [[Austro-Hungarian Army]] and served in the ski corps, and later was transferred to the sanitary corps, for which he set up a laboratory in Trieste. At the end of the war Carl completed his studies, graduating with Gerty in [[1920]]. Carl and Gerty married that year and worked together in clinics in [[Vienna]].

Carl was invited to Graz to work with [[Otto Loewi]] to study the effect of the vagus nerve on the [[heart]], Loewi would receive the Nobel Prize in Physiology or Medicine in [[1936]] for this work. While Carl was in Graz, Gerty remained in Vienna. A year later Carl was offered a position at the State Institute for the Study of Malignant Diseases (now the [[Roswell Park Cancer Institute]]) in Buffalo, New York and the Cori's moved to Buffalo.

While at the Institute the Cori's research focussed on [[carbohydrate metabolism]], leading to the definition of the [[Cori cycle]] in [[1929]], for which they received the Nobel Prize in Physiology or Medicine in 1947. In [[1928]], they became [[naturalized citizen]]s of the United States. In [[1931]] Carl accepted a position at the [[Washington University]] School of Medicine in [[St. Louis, Missouri]]. Carl joined as professor of pharmacology and in [[1942]] was made professor of biochemistry. 

In 1946, he won the [[Albert Lasker Award for Basic Medical Research]].

Gerty died in [[1957]], Carl married Anne Fitz-Gerald Jones in [[1960]]. Carl stayed on at Washington University until 1966, when he retired as chair of the biochemistry department. Following retirement Cori moved to [[Cambridge, Massachusetts]], [[Harvard University]] laboratory space at the Massachusetts General Hospital, where he pursued research in genetics.

Carl shares a star with Gerty on the [[St. Louis Walk of Fame]].

==References==
*Ihde, A.J. Cori, Carl Ferdinand, and Gerty Theresa Radnitz Cori. American National Biography Online Feb 2000.


==External links==
*[http://nobelprize.org/medicine/laureates/1947/cori-cf-bio.html Nobel Prize biography]

{{Nobel Prize in Physiology or Medicine Laureates 1926-1950}}

{{BD|1896|1984|Cori, Carl Ferdinand}}
[[Category:Jewish American scientists]]
[[Category:Austrian-American Jews]]
[[Category:American biochemists]]
[[Category:Naturalized citizens of the United States]]
[[Category:Nobel laureates in Physiology or Medicine]]
[[Category:People from Buffalo, New York]]
[[Category:Washington University in St. Louis faculty]]
[[Category:Recipients of the Albert Lasker Award for Basic Medical Research]]
[[Category:Charles University alumni]]

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[[zh:卡尔·斐迪南·科里]]

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