View source for Mixed disorder of acid-base balance

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{{DiseaseDisorder infobox |
  Name        = Mixed disorder of acid-base balance |
  ICD10       = {{ICD10|E|87|4|e|70}} |
  ICD9        = {{ICD9|276.4}} |
}}
In a '''mixed disorder of acid-base balance''' more than one of the following four primary acid base disorders is occurring in the patient at the same time:

{| class="wikitable"
| '''condition''' || '''[[pH]]''' || '''[[carbon dioxide]]'''  || '''compensation'''
 |- 
 | [[metabolic acidosis]] || down || down || respiratory
 |- 
 | [[respiratory acidosis]] || down || up || renal
 |- 
 | [[metabolic alkalosis]] || up || up || respiratory
 |- 
 | [[respiratory alkalosis]] || up  || down || renal
|}

(Exception: A person cannot have both a respiratory [[acidosis]] and a respiratory [[alkalosis]] at the same time.)

In contrast, with a ''simple acid base disorder'', there is only one of the four primary acid base disorders present. 

The patient can have an acidosis and alkosis at the same time that partially counteract each other, or there can be two different conditions effecting the pH in the same direction. The phrase "mixed acidosis", for example, refers to [[metabolic acidosis]] in conjunction with [[respiratory acidosis]].

There is actually an easy way to identify if the Acid-Base balance disorder is Metabolic or Respiratory in origin. 
* If the pH and Carbon dioxide levels are either both increased or decreased, then it is Metabolic. 
* If the pH level is opposite to that of the Carbon dioxide level or vice versa, then it is Respiratory. 

Determining if it is acidosis or alkalosis depends upon the pH of the blood which is normally regulated between pH 7.35 and 7.45. 
* If pH is above 7.45, then an alkalemia is present - this indicates the presence of an alkalosis. 
* If pH is below 7.35, then an acidemia is present - this indicates the presence of an acidosis.

==See also==
[[Acid base physiology]]

==External links==
* [http://www.lakesidepress.com/pulmonary/ABG/MixedAB.htm Diagnoses at lakesidepress.com]
* [http://www.nda.ox.ac.uk/wfsa/html/u16/u1602_01.htm Interpretation at nda.ox.ac.uk]
* [http://www.anaesthesiamcq.com/AcidBaseBook/ABindex.php Acid Base Tutorial]

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[[Category:Disease]]
[[Category:Physiology]]
[[Category:Inborn errors of metabolism]]