View source for Hyperpituitarism

'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Infobox_Disease
 | Name           = {{PAGENAME}}
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 | ICD10          = {{ICD10|E|22||e|20}} 
 | ICD9           = {{ICD9|253.1}}
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 | eMedicineSubj  = 
 | eMedicineTopic =  
 | MeshID         = D006964
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==Overview==
'''Hyperpituitarism''' is the result of excess secretion of adenohypophyseal trophic [[hormones]] most commonly by a functional [[pituitary adenoma]]. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders. 

==Clinical manifestations==
Depending on the cell type(s) affected, clinical manifestations of hormone excess may include:
*[[Hyperprolactinaemia]]
*[[Cushing's disease]]
*[[Precocious puberty]]
*[[Gigantism]] or [[Acromegaly]]
*[[Hyperthyroidism]] (rare)

==Associated conditions==
When there is an enlargement of the pituitary tissue, hyperpituitarism is often associated with:
*[[Visual field]] defects, classically [[Bitemporal hemianopsia|bitemporal hemianopia]]
*Radiographic abnormalities of the [[sella turcica]], such as sellar expansion, bony erosion and disuption of the [[diaphragma sellae]]
*[[Intracranial pressure#Increased ICP|Increased intracranial pressure]]

==Symptoms==
Symptoms caused by hormone excess and associated mass effects include:
* [[Headache]]
* Visual field loss or [[Double vision]]
* [[Excessive sweating]]
* [[Hoarseness]]
* Milk secretion from [[breast]]
* [[Sleep apnea]]
* [[Carpal tunnel syndrome]]
* [[Joint pain]] and limitation of motion
* [[Muscle weakness]]
* [[Numbness]] or [[tingling of skin]]


{{Endocrine pathology}}

[[Category:Endocrinology]]
[[Category:Mature chapter]]

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