View source for HIP1R

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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image = PBB_Protein_HIP1R_image.jpg
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1r0d.
 | PDB = {{PDB2|1r0d}}
 | Name = Huntingtin interacting protein 1 related
 | HGNCid = 18415
 | Symbol = HIP1R
 | AltSymbols =; ILWEQ; FLJ14000; HIP12; HIP3; KIAA0655; MGC47513
 | OMIM = 605613
 | ECnumber =  
 | Homologene = 78348
 | MGIid = 1352504
 | GeneAtlas_image1 = PBB_GE_HIP1R_209558_s_at_tn.png
 | GeneAtlas_image2 = PBB_GE_HIP1R_209559_at_tn.png
 | GeneAtlas_image3 = PBB_GE_HIP1R_38340_at_tn.png
 | Function = {{GNF_GO|id=GO:0003779 |text = actin binding}} {{GNF_GO|id=GO:0005543 |text = phospholipid binding}} 
 | Component = {{GNF_GO|id=GO:0005905 |text = coated pit}} {{GNF_GO|id=GO:0030136 |text = clathrin-coated vesicle}} 
 | Process = {{GNF_GO|id=GO:0008150 |text = biological_process}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9026
    | Hs_Ensembl = ENSG00000130787
    | Hs_RefseqProtein = XP_001132864
    | Hs_RefseqmRNA = XM_001132864
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 121886051
    | Hs_GenLoc_end = 121913460
    | Hs_Uniprot = O75146
    | Mm_EntrezGene = 29816
    | Mm_Ensembl = ENSMUSG00000000915
    | Mm_RefseqmRNA = NM_145070
    | Mm_RefseqProtein = NP_659507
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 124234381
    | Mm_GenLoc_end = 124263818
    | Mm_Uniprot = Q3UJ14
  }}
}}
'''Huntingtin interacting protein 1 related''', also known as '''HIP1R''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HIP1R huntingtin interacting protein 1 related| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9026| accessdate = }}</ref>

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| summary_text = 
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==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Parker JA, Metzler M, Georgiou J, ''et al.'' |title=Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. |journal=J. Neurosci. |volume=27 |issue= 41 |pages= 11056-64 |year= 2007 |pmid= 17928447 |doi= 10.1523/JNEUROSCI.1941-07.2007 }}
*{{cite journal  | author=Bradley SV, Hyun TS, Oravecz-Wilson KI, ''et al.'' |title=Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. |journal=Hum. Mol. Genet. |volume=16 |issue= 11 |pages= 1279-92 |year= 2007 |pmid= 17452370 |doi= 10.1093/hmg/ddm076 }}
*{{cite journal  | author=Brett TJ, Legendre-Guillemin V, McPherson PS, Fremont DH |title=Structural definition of the F-actin-binding THATCH domain from HIP1R. |journal=Nat. Struct. Mol. Biol. |volume=13 |issue= 2 |pages= 121-30 |year= 2006 |pmid= 16415883 |doi= 10.1038/nsmb1043 }}
*{{cite journal  | author=Provençal N, Shink E, Harvey M, ''et al.'' |title=Analysis of a variable number tandem repeat polymorphism in the huntingtin interacting protein-1 related gene for anticipation in bipolar affective disorder. |journal=Prog. Neuropsychopharmacol. Biol. Psychiatry |volume=28 |issue= 8 |pages= 1299-303 |year= 2005 |pmid= 15588756 |doi= 10.1016/j.pnpbp.2004.07.001 }}
*{{cite journal  | author=Senetar MA, Foster SJ, McCann RO |title=Intrasteric inhibition mediates the interaction of the I/LWEQ module proteins Talin1, Talin2, Hip1, and Hip12 with actin. |journal=Biochemistry |volume=43 |issue= 49 |pages= 15418-28 |year= 2005 |pmid= 15581353 |doi= 10.1021/bi0487239 }}
*{{cite journal  | author=Navarro-Lérida I, Martínez Moreno M, Roncal F, ''et al.'' |title=Proteomic identification of brain proteins that interact with dynein light chain LC8. |journal=Proteomics |volume=4 |issue= 2 |pages= 339-46 |year= 2004 |pmid= 14760703 |doi= 10.1002/pmic.200300528 }}
*{{cite journal  | author=Engqvist-Goldstein AE, Zhang CX, Carreno S, ''et al.'' |title=RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery. |journal=Mol. Biol. Cell |volume=15 |issue= 4 |pages= 1666-79 |year= 2004 |pmid= 14742709 |doi= 10.1091/mbc.E03-09-0639 }}
*{{cite journal  | author=Hyun TS, Rao DS, Saint-Dic D, ''et al.'' |title=HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains. |journal=J. Biol. Chem. |volume=279 |issue= 14 |pages= 14294-306 |year= 2004 |pmid= 14732715 |doi= 10.1074/jbc.M312645200 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Legendre-Guillemin V, Metzler M, Charbonneau M, ''et al.'' |title=HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. |journal=J. Biol. Chem. |volume=277 |issue= 22 |pages= 19897-904 |year= 2002 |pmid= 11889126 |doi= 10.1074/jbc.M112310200 }}
*{{cite journal  | author=Chopra VS, Metzler M, Rasper DM, ''et al.'' |title=HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin. |journal=Mamm. Genome |volume=11 |issue= 11 |pages= 1006-15 |year= 2001 |pmid= 11063258 |doi=  }}
*{{cite journal  | author=Seki N, Muramatsu M, Sugano S, ''et al.'' |title=Cloning, expression analysis, and chromosomal localization of HIP1R, an isolog of huntingtin interacting protein (HIP1). |journal=J. Hum. Genet. |volume=43 |issue= 4 |pages= 268-71 |year= 1999 |pmid= 9852681 |doi=  }}
*{{cite journal  | author=Ishikawa K, Nagase T, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169-76 |year= 1998 |pmid= 9734811 |doi=  }}
*{{cite journal  | author=Puigvert A |title=Caliceal urodynamics. |journal=Urol. Int. |volume=30 |issue= 4 |pages= 282-96 |year= 1976 |pmid= 1189126 |doi=  }}
}}
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