View source for Ketamine

{{DrugProjectFormSinglePage
|authorTag={{chetan}}
|genericName=Ketamine
|aOrAn=a
|drugClass=general anesthetic
|indication=general anesthesia; adjunct, procedural sedation
|adverseReactions=[[cardiovascular]]: [[hypertension]], [[tachycardia]],  [[neurologic]]: emergence from anesthesia, [[psychiatric]] sign or symptom (12% to 50% ).
|blackBoxWarningTitle=<b><span style="color:#FF0000;">TITLE</span></b>
|blackBoxWarningBody=<i><span style="color:#FF0000;">Condition Name:</span></i> (Content)
|fdaLIADAdult=* General anesthesia; adjunct: induction, 1 to 4.5 mg (base)/kg IV single dose
* General anesthesia; adjunct: induction, 1 to 2 mg/kg IV infusion at 0.5 mg/kg/min; in addition to diazepam 2 to 5 mg IV over 1 min
* General anesthesia; adjunct: induction, 6.5 to 13 mg (base)/kg IM
* General anesthesia; adjunct: maintenance, 0.1 to 0.5 mg (base)/min IV infusion, repeat as needed; augmented with diazepam 2 to 5 mg IV
* General anesthesia; adjunct: maintenance, 0.01 to 0.03 mg/kg/min continuous IV infusion
* General anesthesia; adjunct: maintenance, increments of one-half to the full induction dose may be repeated as needed
* Procedural sedation: 1 to 2 mg/kg IV over 1 to 2 min, may be followed by 0.25 to 0.5 mg/kg IV every 5 to 10 min as needed.
* Rapid sequence intubation, Induction: 2 mg/kg IV.
|offLabelAdultGuideSupport=* General anesthesia; Adjunct.
* Procedural sedation.
|offLabelAdultNoGuideSupport=* Administration of analgesic - sedation.
* [[Bronchospasm]].
* Rapid sequence intubation, induction
|fdaLIADPed=* Safety and efficacy have not been established in children younger than 16 years.
* General anesthesia; adjunct: induction, 5 to 10 mg (base)/kg IM; range, 4 to 13 mg/kg.
* General anesthesia; adjunct: induction, 1 to 2 mg/kg IV; range, 0.5 to 4.5 mg/kg.
* General anesthesia; adjunct: maintenance, 0.01 to 0.03 mg/kg/min continuous IV infusion.
* General anesthesia; adjunct: maintenance, increments of one-half to the full induction dose may be repeated as needed.
* Procedural sedation: 0.5 to 2 mg/kg IV over 1 to 2 min, may repeat 0.25 to 1 mg/kg IV (one-half initial dose) every 10 to 15 min as needed.
* Procedural sedation: 2 to 5 mg/kg IM, may repeat 2 to 4 mg/kg after 10 min. 
* Rapid sequence intubation, Induction: 1 to 3 mg/kg IV.
|offLabelPedGuideSupport=There is limited information about <i>Off-Label Guideline-Supported Use</i> of Ketamine in pediatric patients.
|offLabelPedNoGuideSupport=There is limited information about <i>Off-Label Non–Guideline-Supported Use</i> of Ketamine in pediatric patients.
|contraindications=* Ketamine hydrochloride is contraindicated in those in whom a significant elevation of blood pressure would constitute a serious hazard and in those who have shown hypersensitivity to the drug. 
|alcohol=Alcohol-Ketamine interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
}}