View source for 2-Methyl-2-nitrosopropane

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| ImageFile = 2-methyl-2-nitrosopropane-2D-skeletal.png
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| ImageFile1 = 2-methyl-2-nitrosopropane-3D-balls.png
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| IUPACName = 2-Methyl-2-nitrosopropane
| OtherNames = ''t''-Nitrosobutane
| Section1 = {{Chembox Identifiers
| Abbreviations = NMP
| CASNo = 6841-96-9
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| SMILES = CC(C)(C)N=O
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| Formula = C<sub>4</sub>H<sub>9</sub>NO
| MolarMass = 87.12 g/mol
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'''2-Methyl-2-nitrosopropane''' (MNP or t-nitrosobutane, chemical formula (CH<sub>3</sub>)<sub>3</sub>CNO) is a [[spintrap]].  This molecule forms adducts with unstable [[free radicals]] to form a more stable [[paramagnetic]] nitroxide radical that can be detected by [[electron spin resonance]] spectroscopy. It is particularly useful for trapping carbon-centered tyrosyl radicals.<ref>see J. Biol. Chem. 271 (1996), 15498-15503</ref>

MNP is also the aerial oxidation product of t-butylhydroxylamine (NtBHA),  which in turn is a hydrolysis product of phenylbutylnitrone and similar spintraps.   MNP has pharmacological action, both by scavenging free radicals and possibly by releasing the messenger substance [[nitric oxide]] in the presence of light and under oxidizing conditions.<ref>[http://www.nitrone.com]</ref>  Production of NtHBA and its parent spintrap MNP may account for the sometime antistroke action of the drug [[NXY-059]].

MNP is also an efficient regulator of the radical [[polymerization]] of methyl methacrylate through the 'pseudoliving' chain mechanism.<ref>{{Cite journal|author = Dmitry F Grishin,  Lyudmila L Semyonycheva,  Elena V Kolyakina|title=  "2-Methyl-2-nitrosopropane as a new regulator of the polymer chain growth"|journal= Mendeleev Communications|year = 1999|volume=9|issue=6|pages = 250-251}}</ref>

== Notes ==
{{reflist|2}}

==See also==
*[[Nitroso]]

{{DEFAULTSORT:Methyl-2-nitrosopropane, 2-}}
[[Category:Nitroso compounds]]
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