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'''Acid Citrate Dextrose Solution''' (sometimes called Anticoagulant Citrate Dextrose Solution) is a solution of [[citric acid]], [[sodium citrate]] and [[dextrose]] in water.  It is mainly used as an [[anticoagulant]] to preserve blood, it is also used during procedures such as [[plasmapheresis]] instead of [[heparin]].  Two different solutions (Solution A and B) are defined by the [[United States Pharmacopeia]].

They have the following properties:

{|class="wikitable" style="text-align:center"
|+Solution A (per 1000 mL)
|Total Citrate (as [[Citric acid]], anhydrous (C6H8O7)) ||20.59 to 22.75g
|-
|[[Dextrose]] (C6H12O6*H2O) ||23.28g to 25.73g
|-
|[[Sodium]] (Na) ||4.90g to 5.42g
|}

{|class="wikitable" style="text-align:center"
|+Solution B (per 1000 mL)
|Total Citrate (as Citric acid, anhydrous (C6H8O7)) ||12.37 to 13.67g
|-
|Dextrose (C6H12O6*H2O) ||13.96 to 15.44g
|-
|Sodium (Na) ||2.94 to 3.25g
|}

To make use:

{|class="wikitable" style="text-align:center"
|| ||A||B
|-
|Citric Acid, anhydrous (C6H8O7) ||7.3g|| 4.4
|-
|Sodium Citrate, dihydrate  ||22.0g || 13.2
|-
|Dextrose, monohydrate (C6H12O6*H2O) ||24.5g || 14.7
|-
|[[Water]] for Injection to make ||1000 mL||1000 mL
|}

Dissolve the ingredients and mix.  Filter until clear.

== References ==

United States Pharmacopeia 26, 2002, pp 158.

== External links ==

* [http://www.usp.org/ US Pharmacopeia]

[[Category:Anticoagulants]]
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