View source for Ataxin 7

{{infobox protein
| Name = ataxin 7
| caption =
| image =
| width =
| HGNCid = 10560
| Symbol = ATXN7
| AltSymbols = SCA7
| EntrezGene = 6314
| OMIM = 607640
| RefSeq = NM_000333
| UniProt = O15265
| PDB =
| ECnumber =
| Chromosome = 3
| Arm = p
| Band = 21.1
| LocusSupplementaryData = -p12
}}
'''Ataxin 7''' is a [[protein]] associated with both [[olivopontocerebellar atrophy]] type 3 (OPCA3) and [[spinocerebellar ataxia]] type 7 (SCA7).

==External links==
* [https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=sca7  GeneReviews/NCBI/NIH/UW entry on Spinocerebellar Ataxia Type 7]
* {{MeshName|ataxin-7}}
* {{OMIM|164500}}
* {{cite journal | vauthors = Janer A, Martin E, Muriel M, Latouche M, Fujigasaki H, Ruberg M, Brice A, Trottier Y, Sittler A | title = PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins | journal = J Cell Biol | volume = 174 | issue = 1 | pages = 65–76 | year = 2006 | pmid = 16818720 | doi = 10.1083/jcb.200511045 | pmc = 2064165}}
* {{cite journal | vauthors = Helmlinger D, Hardy S, Eberlin A, Devys D, Tora L | title = Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes | journal = Biochem Soc Symp | volume = | issue = 73| pages = 155–63 | year = 2006 | pmid = 16626296}}
* {{cite journal | vauthors = Wang H, Yeh T, Chou A, Kuo Y, Luo L, He C, Huang P, Li A | title = Polyglutamine-expanded ataxin-7 activates mitochondrial apoptotic pathway of cerebellar neurons by upregulating Bax and downregulating Bcl-x(L) | journal = Cell Signal | volume = 18 | issue = 4 | pages = 541–52 | year = 2006 | pmid = 15964171 | doi = 10.1016/j.cellsig.2005.05.024}}
* {{cite journal | vauthors = Ansorge O, Giunti P, Michalik A, Van Broeckhoven C, Harding B, Wood N, Scaravilli F | title = Ataxin-7 aggregation and ubiquitination in infantile SCA7 with 180 CAG repeats | journal = Ann Neurol | volume = 56 | issue = 3 | pages = 448–52 | year = 2004 | pmid = 15349877 | doi = 10.1002/ana.20230}}
* {{cite journal | vauthors = Helmlinger D, Hardy S, Sasorith S, Klein F, Robert F, Weber C, Miguet L, Potier N, Van-Dorsselaer A, Wurtz J, Mandel J, Tora L, Devys D | title = Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes | journal = Hum Mol Genet | volume = 13 | issue = 12 | pages = 1257–65 | year = 2004 | pmid = 15115762 | doi = 10.1093/hmg/ddh139}}

{{Nucleus}}

[[Category:Proteins]]


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