View source for CCL25

{{protein
| Name = chemokine (C-C motif) ligand 25
| caption = 
| image = 
| width = 
| HGNCid = 10624
| Symbol = CCL25
| AltSymbols = SCYA25, TECK, Ckb15
| EntrezGene = 6370
| OMIM = 602565
| RefSeq = NM_005624
| UniProt = O15444
| PDB = 
| ECnumber = 
| Chromosome = 19
| Arm = p
| Band = 13.2
| LocusSupplementaryData = 
}}

'''Chemokine (C-C motif) ligand 25''' (CCL25) is a small [[cytokine]] belonging to the CC [[chemokine]] family that is also known as TECK (Thymus-Expressed Chemokine).  CCL25 is believed to play a role in the development of [[T-cell]]s.<ref>Vacari et al., TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. Immunity, 1997, 7:291-301.</ref> It is [[chemotactic]] for [[thymocyte]]s, [[macrophage]]s, and [[dendritic cell]]s. CCL25 elicits its effects by binding to the [[chemokine receptor]] [[CC chemokine receptors#CCR9|CCR9]].<ref>Zaballos et al., Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J. Immunol., 1999, 162:5671-5675.</ref><ref>Gosling et al., Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK. J Immunol. 2000, 164:2851-6.</ref>  Human CCL25 is produced as a [[protein precursor]] containing 151 [[amino acid]]s.  The gene for CCL25 (''scya25'') is located on human chromosome 19.<ref>Nomiyama et al., The human CC chemokine TECK (SCYA25) maps to chromosome 19p13.2. Genomics, 1998, 51:311-312.</ref>

==References==
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{{Chemokines}}
{{Chemokine receptor modulators}}

[[Category:Cytokines]]


{{gene-19-stub}}