View source for CXCL15

{{Infobox_gene}}

'''Chemokine (C-X-C motif) ligand 15''' (CXCL15) is a small [[cytokine]] belonging to the CXC [[chemokine]] family that has been described in the mouse.  This chemokine is also known under the name ''lungkine''. CXCL15 is an ELR+ CXC chemokine (it contains the [[amino acid]] sequence E-L-R immediately before its CXC motif) that recruits [[neutrophil]]s during inflammation of the [[lung]]s.  It is highly abundant in [[epithelial cell]]s of the lung,<ref>{{cite journal |vauthors=Rossi D, Hurst S, Xu Y, Wang W, Menon S, Coffman R, Zlotnik A |title=Lungkine, a novel CXC chemokine, specifically expressed by lung bronchoepithelial cells |journal=J Immunol |volume=162 |issue=9 |pages=5490–7 |year=1999 |pmid=10228029}}</ref> and can also be found in other [[Mucous membrane|mucosal organs]] such as the [[urogenital]] and [[gastrointestinal tract]]s, and in [[endocrine]] organs like the [[adrenal gland]].<ref>{{cite journal |vauthors=Schmitz J, McCracken V, Dimmitt R, Lorenz R |title=Expression of CXCL15 (Lungkine) in Murine Gastrointestinal, Urogenital, and Endocrine Organs |journal=J Histochem Cytochem |volume= 55|issue= 5|pages= 515–24|year= 2007|pmid=17242461 |doi=10.1369/jhc.6A7121.2007}}</ref> The [[gene]] for CXCL15 is found on mouse [[chromosome]] 5.

==References==
{{Reflist}}


{{Chemokines}}
{{Chemokine receptor modulators}}

[[Category:Cytokines]]


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