View source for Familial male precocious puberty

'''Familial male precocious puberty''' (also known as '''testotoxicosis''') is a form of [[gonadotropin]]-independent [[precocious puberty]] in which boys experience early onset and progression of [[puberty]]. Signs of puberty can develop as early as an age of 1 year.

The ﬁnal length of boys may be short due to a rapid advance in epiphyseal maturation. It is an [[autosomal dominant]] condition with a [[mutation]] of the [[LH receptor]]. Treatment is with drugs that suppress gonadal [[steroidogenesis]], such as [[cyproterone acetate]], [[ketoconazole]] or [[spironolactone]] and
[[testolactone]].

==References==
* {{cite journal | author=Traggiai C, Stanhope R | title=Disorders of pubertal development | journal=Best Pract Res Clin Obstet Gynaecol | year=2003 | pages=41-56 | volume=17 | issue=1  | id=PMID 12758225}}
* {{cite journal | author=Reiter EO, Norjavaara E | title=Testotoxicosis: current viewpoint | journal=Pediatr Endocrinol Rev | year=2005 | pages=77-86 | volume=3 | issue=2  | id=PMID 16361981}}

==External links==
* {{OMIM|176410}}
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[[Category:Disease]]