View source for HLA-B42



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| align="center" colspan="2" |  
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| align="center" colspan="2" | <div style="font-size:medium; line-height:120%;">major histocompatibility complex (human), class I, B42</div>
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| bgcolor="#e7dcc3" | Alleles  
| bgcolor="#eeeeee" | B*4201 </br> B*4202 </br>
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| colspan="2" bgcolor="#dddddd" | '''Structure''' (See [[HLA-B]])
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| bgcolor="#e7dcc3" | [[HUGO|Symbol(s)]]
| bgcolor="#eeeeee" | [http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4932 HLA-B] 
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| bgcolor="#e7dcc3" | [[European Bioinformatics Institute|EBI-HLA]]
| bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?B*4201 B*4201]
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| bgcolor="#e7dcc3" | [[European Bioinformatics Institute|EBI-HLA]]
| bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?B*4202 B*4202]
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| bgcolor="#e7dcc3" | [[Locus (genetics)|Locus]] 
| bgcolor="#eeeeee" | [[Chromosome 6 (human)|chr.6]] ''[http://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31]''
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'''HLA-B42''' (B42) is an [[Human leukocyte antigen|HLA]]-[[HLA-B|B]] [[serotype]]. The serotype identifies the HLA-B*4201 and *4202 gene products.<ref name="pmid15787720">{{cite journal | author = Marsh SG, Albert ED, Bodmer WF, ''et al'' | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x}}</ref> HLA-B*4201 is common Central Africa.   (For terminology help see: [[HLA-A#Historical Guide to Understanding Nomenclature|HLA-serotype tutorial]]) 

==Serotype==
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|+ B42 serotype recognition of Some HLA B*42 allele-group gene products<ref>[http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]</ref>
|- style="background:#f0f0ff"
| style="width:60px" | B*42 || style="width:60px" | '''B42''' 
| style="width:60px" | other    || style="width:60px" | Sample
|- style="background:#f0f0ff"
| allele || % || % || size (N)
|- 
| style = "background:#e8e8f8" | 4201 || 93 || 2 || 1015 
|- 
| style = "background:#e8e8f8" | 4202 || 95 ||  || 80 
|}

Serological typing for B*4201 and B*4202 is relatively efficient. 
<br/>
<br/>
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===B*4201 allele frequencies===

{|border="0" cellspacing="0" cellpadding="1" align="right" style="text-align:center; margin-left: 2em;  border:1px #ffeebb solid; background:#f8f6f8; "
|+ '''HLA B*4201 frequencies'''
|- style="background:#efe5ef"
|  ||   || freq 
|- style="background:#eee5ef"
| ref. || align="left" |Population || style="width:50px" | (%)
|-
| <ref name = "pmid12753660">{{cite journal | author = Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database: http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403-7 | year = 2003 | pmid = 12753660 | doi = }}</ref>  || align="left"|Zambia Lusaka||14.8
|-
| <ref name = "pmid12753660"/> || align="left"|Mali Bandiagara||13.8
|-
| <ref name = "pmid12753660"/> || align="left"|Burkina Faso Mossi||13.2
|-
| <ref name = "pmid12753660"/> || align="left"|South Africian Natal Zulu||12.0
|-
| <ref name = "pmid12753660"/> || align="left"|Burkina Faso Rimaibe||9.6
|-
| <ref name = "pmid12753660"/> || align="left"|South Africa Tswana||8.5
|-
| <ref name = "pmid12753660"/> || align="left"|Kenya Luo||7.7
|-
| <ref name = "pmid12753660"/> || align="left"|Kenya ||7.3
|-
| <ref name = "pmid12753660"/> || align="left"|Kenya Nandi||6.9
|-
| <ref name = "pmid12753660"/> || align="left"|Zimbabwe Harare Shona||6.9
|-
| <ref name = "pmid12753660"/> || align="left"|Saudi Arabia||5.6
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Yaounde||4.9
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Beti||4.0
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Bamileke||3.9
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Sawa||3.8
|-
| <ref name = "pmid12753660"/> || align="left"|Ivory Coast Akan Adiopodoume||3.4
|-
| <ref name = "pmid12753660"/> || align="left"|Israel Gaza Palestinians||2.4
|-
| <ref name = "pmid12753660"/> || align="left"|India North Delhi||2.2
|-
| <ref name = "pmid12753660"/> || align="left"|Senegal Niokholo Mandenka||1.6
|-
| <ref name = "pmid12753660"/> || align="left"|Mbenzele Pygmy (C. Afr. Rep.)||1.5
|-
| <ref name = "pmid12753660"/> || align="left"|Iran Baloch||1.5
|-
| <ref name = "pmid12753660"/> || align="left"|Pakistan Baloch||1.5
|-
| <ref name = "pmid12753660"/> || align="left"|Sudanese||1.5
|-
| <ref name = "pmid12753660"/> || align="left"|Tunisia||1.5
|-
| <ref name = "pmid12753660"/> || align="left"|Pakistan Brahui||1.4
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Bamileke||1.3
|-
| <ref name = "pmid12753660"/> || align="left"|Oman||1.3
|-
| <ref name = "pmid12753660"/> || align="left"|Sudanese||1.3
|-
| <ref name = "pmid12753660"/> || align="left"|Tunisia Tunis||1.1
|-
| <ref name = "pmid12753660"/> || align="left"|Zimbabwe Harare Shona||1.1
|-
| <ref name = "pmid12753660"/> || align="left"|Cameroon Bakola Pygmy||1.0
|-
| <ref name = "pmid12753660"/> || align="left"|Pakistan Pathan||1.0
|-
| <ref name = "pmid12753660"/> || align="left"|Portugal Centre||1.0
|-
| <ref name = "pmid12753660"/> || align="left"|Saudi Arabia Guraiat and Hail||1.0
|-
| <ref name = "pmid12753660"/> || align="left"|Morocco Casablanca||0.9
|-
| <ref name = "pmid12753660"/> || align="left"|Senegal Dakar||0.9
|-
| <ref name = "pmid12753660"/> || align="left"|Uganda Kampala||0.9
|-
| <ref name = "pmid12753660"/> || align="left"|Cape Verde Southeastern Islands||0.8
|-
| <ref name = "pmid12753660"/> || align="left"|Guinea Bissau||0.8
|-
| <ref name = "pmid12753660"/> || align="left"|United Arab Emerates||0.8
|-
| <ref name = "pmid12753660"/> || align="left"|Morocco Nador Metalsa Class I||0.7
|-
| <ref name = "pmid12753660"/> || align="left"|Pakistan Karachi Parsi||0.6
|-
| <ref name = "pmid12753660"/> || align="left"|Spain Majorca||0.6
|-
| <ref name = "pmid12753660"/> || align="left"|China Yunnan Han pop2||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|England Newcastle||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Israel Arab Druse||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Israel Jews||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Italy Rome||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Guadalajara Mestizos (2) (Mexico) ||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Morocco||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Pakistan Sindhi||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Senegal Niokholo Mandenka||0.5
|-
| <ref name = "pmid12753660"/> || align="left"|Singapore Riau Malay||0.5
|}

==References==
<div class="references-small"><references/></div>
[[Category:HLA-B alleles|4]]
{{HLAB}}

[[Category:Proteins]]

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