View source for HRSP12

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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image = PBB_Protein_HRSP12_image.jpg
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1oni.
 | PDB = {{PDB2|1oni}}
 | Name = Heat-responsive protein 12
 | HGNCid = 16897
 | Symbol = HRSP12
 | AltSymbols =; PSP; P14.5; UK114
 | OMIM = 602487
 | ECnumber =  
 | Homologene = 4261
 | MGIid = 1095401
 | GeneAtlas_image1 = PBB_GE_HRSP12_203790_s_at_tn.png
 | Function = {{GNF_GO|id=GO:0004519 |text = endonuclease activity}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}} 
 | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} 
 | Process = {{GNF_GO|id=GO:0006449 |text = regulation of translational termination}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10247
    | Hs_Ensembl = ENSG00000132541
    | Hs_RefseqProtein = NP_005827
    | Hs_RefseqmRNA = NM_005836
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 99183743
    | Hs_GenLoc_end = 99198594
    | Hs_Uniprot = P52758
    | Mm_EntrezGene = 15473
    | Mm_Ensembl = ENSMUSG00000022323
    | Mm_RefseqmRNA = NM_008287
    | Mm_RefseqProtein = NP_032313
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 15
    | Mm_GenLoc_start = 34428610
    | Mm_GenLoc_end = 34439769
    | Mm_Uniprot = Q569N4
  }}
}}
'''Heat-responsive protein 12''', also known as '''HRSP12''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HRSP12 heat-responsive protein 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10247| accessdate = }}</ref>

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==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Mistiniene E, Pozdniakovaite N, Popendikyte V, Naktinis V |title=Structure-based ligand binding sites of protein p14.5, a member of protein family YER057c/YIL051c/YjgF. |journal=Int. J. Biol. Macromol. |volume=37 |issue= 1-2 |pages= 61-8 |year= 2006 |pmid= 16198412 |doi= 10.1016/j.ijbiomac.2005.08.008 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Manjasetty BA, Delbrück H, Pham DT, ''et al.'' |title=Crystal structure of Homo sapiens protein hp14.5. |journal=Proteins |volume=54 |issue= 4 |pages= 797-800 |year= 2004 |pmid= 14997576 |doi= 10.1002/prot.10619 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Kanouchi H, Oka T, Asagi K, ''et al.'' |title=Expression and cellular distribution of perchloric acid-soluble protein is dependent on the cell-proliferating states of NRK-52E cells. |journal=Cell. Mol. Life Sci. |volume=57 |issue= 7 |pages= 1103-8 |year= 2000 |pmid= 10961346 |doi=  }}
*{{cite journal  | author=Morishita R, Kawagoshi A, Sawasaki T, ''et al.'' |title=Ribonuclease activity of rat liver perchloric acid-soluble protein, a potent inhibitor of protein synthesis. |journal=J. Biol. Chem. |volume=274 |issue= 29 |pages= 20688-92 |year= 1999 |pmid= 10400702 |doi=  }}
*{{cite journal  | author=Colombo I, Ceciliani F, Ronchi S, ''et al.'' |title=cDNA cloning and Escherichia coli expression of UK114 tumor antigen. |journal=Biochim. Biophys. Acta |volume=1442 |issue= 1 |pages= 49-59 |year= 1998 |pmid= 9767104 |doi=  }}
*{{cite journal  | author=Racca S, Di Carlo F, Bartorelli A, ''et al.'' |title=Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114. |journal=Virchows Arch. |volume=431 |issue= 5 |pages= 323-8 |year= 1998 |pmid= 9463573 |doi=  }}
*{{cite journal  | author=Schmiedeknecht G, Büchler C, Schmitz G |title=A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1. |journal=Biochem. Biophys. Res. Commun. |volume=241 |issue= 1 |pages= 59-67 |year= 1998 |pmid= 9405234 |doi= 10.1006/bbrc.1997.7772 }}
*{{cite journal  | author=Schmiedeknecht G, Kerkhoff C, Orsó E, ''et al.'' |title=Isolation and characterization of a 14.5-kDa trichloroacetic-acid-soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation. |journal=Eur. J. Biochem. |volume=242 |issue= 2 |pages= 339-51 |year= 1997 |pmid= 8973653 |doi=  }}
*{{cite journal  | author=Oka T, Tsuji H, Noda C, ''et al.'' |title=Isolation and characterization of a novel perchloric acid-soluble protein inhibiting cell-free protein synthesis. |journal=J. Biol. Chem. |volume=270 |issue= 50 |pages= 30060-7 |year= 1996 |pmid= 8530410 |doi=  }}
}}
{{refend}}

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