View source for Mycobacterium intracellulare

{{Taxobox	
| color = lightgrey
| name = ''Mycobacterium intracellulare''
| regnum = [[Bacterium|Bacteria]]
| phylum = [[Actinobacteria]]
| ordo = [[Actinomycetales]]
| subordo = [[Corynebacterineae]]
| familia = [[Mycobacterium|Mycobacteriaceae]]
| genus = ''[[Mycobacterium]]''
| species = '''''M. intracellulare'''''
| binomial = ''Mycobacterium intracellulare''
| binomial_authority = Runyon 1965,  ATCC 13950
}}
{{SI}}
{{EH}}

'''''Mycobacterium intracellulare'''''<br />

==Description==
Gram-positive, nonmotile and acid-fast short to long rods.

'''Colony characteristics'''
*Usually smooth, rarely rough and nonpigmented colonies. Ageing colonies may become yellow.

'''Physiology'''
*Growth on Löwenstein-Jensen medium and Middlebrook 7H10 at 37°C after 7 or more days.
*Resistant to isoniazid, ethambutol, rifampin and streptomycin.

'''Differential characteristics'''
*M. intracellulare and M. avium form the M. avium-intracellulare complex (MAIC). A commercially available [[nucleic acid hybridization|hybridisation]] assay (AccuProbe) to identify all members of the MAIC exists. Furthermore, separate AccuProbes are available to identify either M. intracellulare or M. avium.
*remarkable ITS heterogeneity within different M. intracellulare isolates.

==Pathogenesis==
*Most frequently encountered in [[pulmonary]] secretions from patients suffering from [[tuberculosis]] like disease and from surgical specimens from such patients. 
*When isolated from human [[secretions]], it is often the [[etiologic]] agent of pulmonary disease, although frequently isolated as apparent casual resident 
*[[Biosafety level]] 2

==Type Strain==
*First isolated from fatal systemic disease in a child.  Found in soil and water.
Strain ATCC 13950 = CCUG 28005 = CIP 104243 = DSM 43223 = JCM 6384 = NCTC 13025.

==References==
<references/>
*'''Cuttino, J., A. McCabe'''. 1949. Pure granulomatous nocardiosis: A new fungus disease distinguished by intracellular parasitism. American Journal of Clinical Pathology, 25, 1-34.
*'''Runyon, E.''' 1965. Pathogenic mycobacteria. Advances in Tuberculosis Research, 14, 235-287.

</br>
[[de:Mycobacterium intracellulare]]
[[nl:Mycobacterium intracellulare]]

{{SIB}}

[[Category:Acid fast bacilli]]
[[Category:Actinobacteria]]
[[Category:Nontuberculous mycobacteria]]
[[Category:Gram positive bacteria]]

{{WikiDoc Help Menu}}
{{WikiDoc Sources}}