View source for P11 protein

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'''p11''' is a [[protein]] found in the [[brain]] of [[human]]s and other [[mammal]]s which has been implicated in the regulation of [[emotional mood | mood]]. A [[mouse]] study from 2006 found that low levels of p11 are likely to prevent the raising of [[serotonin]] levels from immediately curing [[clinical depression]]. The protein is thus a strong candidate target molecule for new [[antidepressant | antidepressant drugs]].

==See also==
*[[Biochemistry]]
*[[Neuroscience]]

==References==
*Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, Yacoubi ME, Vaugeois JM, Nomikos GG, Greengard P. "Alterations in 5-HT1B receptor function by p11 in depression-like states". ''Science'' 2006;311(5757):77–80. PMID 16400147

==External links==
*[http://www.npr.org/templates/story/story.php?storyId=5133423 Associated story] on U.S. [[National Public Radio]]
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[[Category:Biomolecules]]

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[[nl:P11]]
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