View source for PCDH10

{{Infobox_gene}}
'''Protocadherin-10''' is a [[protein]] that in humans is encoded by the ''PCDH10'' [[gene]].<ref name="pmid10835267">{{cite journal |vauthors=Nollet F, Kools P, van Roy F | title = Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members | journal = J Mol Biol | volume = 299 | issue = 3 | pages = 551–72 |date=Jul 2000 | pmid = 10835267 | pmc =  | doi = 10.1006/jmbi.2000.3777 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCDH10 protocadherin 10| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57575| accessdate = }}</ref>

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| section_title = 
| summary_text = This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.<ref name="entrez" />
}}

==References==
{{reflist}}

==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  |vauthors=Yagi T, Takeichi M |title=Cadherin superfamily genes: functions, genomic organization, and neurologic diversity |journal=Genes Dev. |volume=14 |issue= 10 |pages= 1169–80 |year= 2000 |pmid= 10817752 |doi=  10.1101/gad.14.10.1169}}
*{{cite journal  |vauthors=Cross SH, Charlton JA, Nan X, Bird AP |title=Purification of CpG islands using a methylated DNA binding column |journal=Nat. Genet. |volume=6 |issue= 3 |pages= 236–44 |year= 1994 |pmid= 8012384 |doi= 10.1038/ng0394-236 }}
*{{cite journal  |vauthors=Wu Q, Maniatis T |title=A striking organization of a large family of human neural cadherin-like cell adhesion genes |journal=Cell |volume=97 |issue= 6 |pages= 779–90 |year= 1999 |pmid= 10380929 |doi=10.1016/S0092-8674(00)80789-8  }}
*{{cite journal  |vauthors=Wu Q, Maniatis T |title=Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3124–9 |year= 2000 |pmid= 10716726 |doi= 10.1073/pnas.060027397  | pmc=16203 }}
*{{cite journal  | author=Nagase T |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=7 |issue= 1 |pages= 65–73 |year= 2000 |pmid= 10718198 |doi=10.1093/dnares/7.1.65  |name-list-format=vanc| author2=Kikuno R  | author3=Ishikawa KI  | display-authors=3  | last4=Hirosawa  | first4=M  | last5=Ohara  | first5=O  }}
*{{cite journal  | author=Wu Q |title=Comparative DNA Sequence Analysis of Mouse and Human Protocadherin Gene Clusters |journal=Genome Res. |volume=11 |issue= 3 |pages= 389–404 |year= 2001 |pmid= 11230163 |doi= 10.1101/gr.167301  | pmc=311048  |name-list-format=vanc| author2=Zhang T  | author3=Cheng JF  | display-authors=3  | last4=Kim  | first4=Y  | last5=Grimwood  | first5=J  | last6=Schmutz  | first6=J  | last7=Dickson  | first7=M  | last8=Noonan  | first8=JP  | last9=Zhang  | first9=MQ }}
*{{cite journal  |vauthors=Wolverton T, Lalande M |title=Identification and characterization of three members of a novel subclass of protocadherins |journal=Genomics |volume=76 |issue= 1–3 |pages= 66–72 |year= 2001 |pmid= 11549318 |doi= 10.1006/geno.2001.6592 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Ying J |title=Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation |journal=Oncogene |volume=25 |issue= 7 |pages= 1070–80 |year= 2006 |pmid= 16247458 |doi= 10.1038/sj.onc.1209154  |name-list-format=vanc| author2=Li H  | author3=Seng TJ  | display-authors=3  | last4=Langford  | first4=C  | last5=Srivastava  | first5=G  | last6=Tsao  | first6=S W  | last7=Putti  | first7=T  | last8=Murray  | first8=P  | last9=Chan  | first9=A T C }}
}}
{{refend}}

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