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The Reference Sequence ('''RefSeq''') [[sequence database|database]] is an [[open access]], annotated collection of publicly available [[nucleotide]] sequences (DNA, RNA) and their [[protein]] translations. This database is built by [[National Center for Biotechnology Information]] (NCBI), and, unlike [[GenBank]], provides only one example of each natural biological molecule for major organisms ranging from viruses to bacteria to eukaryotes. 

For each [[model organism]], ''RefSeq'' aims to provide separate and linked records for the genomic DNA, the gene transcripts, and the proteins arising from those transcripts. ''RefSeq'' is limited to major organisms for which sufficient data is available (almost 4,000 distinct “named” organisms as of January 2007), while [[GenBank]] includes sequences for any organism submitted (approximately 250,000 different named organisms).

==See also==
* [[GenBank]]
* [[Sequence analysis]]
* [[Sequence profiling tool]]
* [[Sequence motif]]
* [[UniProt]]
* [[List of sequenced eukaryotic genomes]]
* [[List of sequenced archeal genomes]]

==External links==
* [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=handbook.section.GenBank_ASM GenBank, RefSeq, TPA and UniProt: What’s in a Name?]

==Sources==
*{{NCBI-handbook}}

[[Category:Bioinformatics databases]]

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