View source for Rose bengal sodium

{{DrugProjectFormSinglePage
|authorTag={{RB}}
|genericName=Rose bengal sodium
|aOrAn=a
|drugClass=[[Diagnosis|Diagnostic Agent]]
|indicationType=diagnosis
|indication=[[keratoconjunctivitis sicca]], [[keratitis]], [[abrasions]] or [[corrosions]] and routine [[ocular]] examinations
|adverseReactions=[[stinging]], [[irritation]], [[discomfort]]



<!--Black Box Warning-->
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>a
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>



<!--Adult Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=====Indications====
* Rose Bengal [[ophthalmic]] strips are used as a [[Diagnosis|diagnostic agent]] in routine [[ocular]] examinations or when superficial [[conjunctiva]] or [[Cornea|corneal tissue change]] is suspected. Rose Bengal ophthalmic strips can also serve as an effective aid in the diagnosis of [[keratoconjunctivitis sicca]], [[keratitis]], [[abrasions]] or [[corrosions]] as well as the detection of [[foreign bodies]].

====Direction====
* To ensure optimal staining and patient comfort, the GloStrip impregnated tip should be moistened with one or two drops of sterile, [[isotonic]] saline or irrigating solution before application. Shake off excess solution and touch [[conjunctiva]] or [[fornix]] as required with moistened tip. It is recommended that the patient blink several times after application.
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Pediatric Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed=There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.

<!--Off-Label Use and Dosage (Pediatric)-->

<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Contraindications-->
|contraindications=* Known [[hypersensitivity]] to Rose Bengal.

<!--Warnings-->
|warnings=* The contents may not be sterile if the individual strip package has been damaged or previously opened. This product is intended for external use only. Keep out of reach of children

<!--Adverse Reactions-->

<!--Clinical Trials Experience-->
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.



<!--Postmarketing Experience-->
|postmarketing=stinging, [[irritation]], [[discomfort]]
|drugInteractions=<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.

<!--Administration and Monitoring-->
|administration=* [[Ophthalmic]]
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.



<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.

<!--Overdosage-->
|overdose=There is limited information regarding <i>Overdose</i> of {{PAGENAME}} in the drug label.

<!--Pharmacology-->

<!--Drug box 2-->
|drugBox={{chembox2
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 417216360
| ImageFile = Rose wiki str.png
| ImageSize =
| IUPACName = <small>4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3''H''- spiro[isobenzofuran-1,9'-xanthen]-3-one</small>
| OtherNames = C.I. 45440
| Section1 = {{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 11121-48-5
| PubChem =
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1160160
| ATCCode_prefix = S01
| ATCCode_suffix = JA02
| SMILES = O=C(O1)C2=C(C(Cl)=C(Cl)C(Cl)=C2Cl)C31C4=C(C(I)=C(O)C(I)=C4)OC5=C(I)C(O)=C(I)C=C53
}}
| Section2 = {{Chembox Properties
 | Formula =
 | C=20 | H=4| Cl=4 | I=4 | O=5
 | MolarMass = 973.67&nbsp;g/mol<br>1,017.65&nbsp;g/mol  (sodium salt)
 | Appearance =
 | Density =
 | MeltingPt =
 | BoilingPt =
 | Solubility = }}
| Section3 = {{Chembox Hazards
 | MainHazards =
 | FlashPt =
 | Autoignition = }}
}}



<!--Mechanism of Action-->
|mechAction=* As a vital stain, Rose Bengal stains both the nuclei and cell walls of dead or degenerated epithelial cells of the [[cornea]] and [[conjunctiva]]. Rose Bengal will also stain the mucus of the precorneal tear film.

<!--Structure-->
|structure=* Rose Bengal Ophthalmic Strips

* diagnostic agent is for professional use only

* Each strip is impregnated with 1.3 mg of Rose Bengal.



<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.

<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.

<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.

<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.

<!--How Supplied-->
|howSupplied=* Dispenser carton containing 100 sterile strips.
|storage=* Store below 30°C.
* Take care not to stain clothing.
|packLabel=====PRINCIPAL DISPLAY PANEL - 100 STRIP CARTON====
: [[File:Rose PDP.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]

====Ingredients and Appearance====
: [[File:Rose I n A.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]

<!--Patient Counseling Information-->
|fdaPatientInfo=====INSTRUCTIONS FOR USE====

: [[File:Rose IFU.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

<!--Brand Names-->
|brandNames=* GLOSTRIPS®<ref>{{Cite web | title = Rose bengal sodium | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d5107c6-5077-4006-994f-1cd351775b80}}</ref>

<!--Look-Alike Drug Names-->
|lookAlike=* There is limited information regarding the look alike drug names

<!--Drug Shortage Status-->
|drugShortage=
}}




<!--Category-->

[[Category:Drug]]