View source for Sip4p gene transcriptions

{{AE}} Henry A. Hoff

The UAS sequence for the transcription factor Sip4p is CCRTYCRTCCG, which occurs in the promoters of ''FBP1, PKC1, ICL1'' genes in ''S. cerevisiae'', with no inducer, used for positive regulation of gluconeogenesis.<ref name=Tang>{{ cite journal
|author=Hongting Tang, Yanling Wu, Jiliang Deng, Nanzhu Chen, Zhaohui Zheng, Yongjun Wei, Xiaozhou Luo, and Jay D. Keasling
|title=Promoter Architecture and Promoter Engineering in ''Saccharomyces cerevisiae''
|journal=Metabolites
|date=6 August 2020
|volume=10
|issue=8
|pages=320-39
|url=https://www.mdpi.com/2218-1989/10/8/320/pdf
|arxiv=
|bibcode=
|doi=10.3390/metabo10080320
|pmid=32781665
|accessdate=18 September 2020 }}</ref>

==Human genes==
{{main|Human genes}}

==Gene expressions==
{{main|Gene expressions}}

==Interactions==
{{main|Interaction gene transcriptions}}

==Consensus sequences==
{{main|Consensus sequence gene transcriptions}}
Sip4p consensus sequence is CC(C/G)T(C/T)C(C/G)TCCG.<ref name=Tang/>

==Binding site for==

Positive regulation of gluconeogenesis.<ref name=Tang/>

==Promoter occurrences==
{{main|Promoter occurrence gene transcriptions}}
Occurs in the promoters of ''FBP1, PKC1, ICL1'' genes in ''S. cerevisiae''.<ref name=Tang>

==Hypotheses==
{{main|Hypotheses}}
# A1BG has no regulatory elements in either promoter.
# A1BG is not transcribed by a regulatory element.
# No regulatory element participates in the transcription of A1BG.

==SIP samplings==
{{main|Model samplings}}
Copying a responsive elements consensus sequence CC(C/G)T(C/T)C(C/G)TCCG and putting the sequence in "⌘F" finds none between ZNF497 and A1BG or none between ZSCAN22 and A1BG as can be found by the computer programs.

For the Basic programs testing consensus sequence CC(C/G)T(C/T)C(C/G)TCCG (starting with SuccessablesSIP.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
# negative strand, negative direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
# positive strand, negative direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
# positive strand, positive direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
# negative strand, positive direction, looking for CC(C/G)T(C/T)C(C/G)TCCG, 0.
# complement, negative strand, negative direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
# complement, positive strand, negative direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
# complement, positive strand, positive direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
# complement, negative strand, positive direction, looking for GG(C/G)A(A/G)G(C/G)AGGC, 0.
# inverse complement, negative strand, negative direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
# inverse complement, positive strand, negative direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
# inverse complement, positive strand, positive direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
# inverse complement, negative strand, positive direction, looking for CGGA(C/G)G(A/C)A(C/G)GG, 0.
# inverse negative strand, negative direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
# inverse positive strand, negative direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
# inverse positive strand, positive direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.
# inverse negative strand, positive direction, looking for GCCT(C/G)C(C/T)T(C/G)CC, 0.

==Acknowledgements==

The content on this page was first contributed by: Henry A. Hoff.

==See also==
{{div col|colwidth=20em}}
* [[A1BG gene transcription core promoters]]
* [[A1BG gene transcriptions]]
* [[A1BG regulatory elements and regions]]
* [[A1BG response element negative results]]
* [[A1BG response element positive results]]
* [[Carbon source-responsive element gene transcriptions]]
* [[Cat8p gene transcriptions]]
* [[Complex locus A1BG and ZNF497]]
{{Div col end}}

==References==
{{reflist|2}}

==External links==
* [http://www.genome.jp/ GenomeNet KEGG database]
* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene Home - Gene - NCBI]
* [http://www.ncbi.nlm.nih.gov/sites/gquery NCBI All Databases Search]
* [http://www.ncbi.nlm.nih.gov/ncbisearch/ NCBI Site Search]
* [http://www.ncbi.nlm.nih.gov/pccompound PubChem Public Chemical Database]

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