View source for Template:Leukotriene signaling modulators

{{Navbox
| name  = Leukotriene signaling modulators
| title = [[Leukotriene]] [[cell signaling|signaling]] [[receptor modulator|modulator]]s
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| bodyclass = hlist
| groupstyle = text-align:center;

| group1 = [[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligand]]s)</small>
| list1 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 4em;

  | group1 = {{abbrlink|BLT|Leukotriene B4 receptor}}
  | list1  = {{Navbox|subgroup
  | groupstyle = text-align:center;
  | groupwidth = 4em;

    | group1 = {{abbrlink|BLT<sub>1</sub>|Leukotriene B4 receptor 1}}
    | list1  =
* '''Agonists:''' [[12-Hydroxyeicosatetraenoic acid|12-HETE]]
* [[20-Hydroxy-LTB4|20-Hydroxy-LTB<sub>4</sub>]]
* [[Leukotriene B4|Leukotriene B<sub>4</sub>]]
* [[LY-255283]]

* '''Antagonists:''' [[20-Carboxy-LTB4|20-Carboxy-LTB<sub>4</sub>]]
* [[Amelubant]]
* [[CGS-23131|CGS-23131 (LY-223982)]]
* [[CGS-25019C]]
* [[CP-105696]]
* [[CP-195543]]
* [[Etalocib]]
* [[LY-293111]]
* [[Moxilubant]]
* [[ONO-4057]]
* [[RG-14893]]
* [[RP-69698]]
* [[SB-209247]]
* [[SC-53228]]
* [[Ticolubant]]
* [[U-75302]]
* [[ZK-158252]]

    | group2 = {{abbrlink|BLT<sub>2</sub>|Leukotriene B4 receptor 2}}
    | list2  =
* '''Agonists:''' [[12-Hydroxyeicosatetraenoic acid|12-HETE]]
* [[12-Hydroxyheptadecatrienoic acid|12-HHT]]
* [[12-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid|12-HpETE]]
* [[15-Hydroxyicosatetraenoic acid|15-HETE]]
* [[15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid|15-HpETE]]
* [[20-Hydroxy-LTB4|20-Hydroxy-LTB<sub>4</sub>]]
* [[Leukotriene B4|Leukotriene B<sub>4</sub>]]

* '''Antagonists:''' [[CP-195543]]
* [[LY-255283]]
* [[ZK-158252]]

  }}

  | group2 = {{abbrlink|CysLT|Cysteinyl leukotriene receptor}}
  | list2  = {{Navbox|subgroup
  | groupstyle = text-align:center;
  | groupwidth = 4em;

    | group1 = {{abbrlink|CysLT<sub>1</sub>|Cysteinyl leukotriene receptor 1}}
    | list1  =
* '''Agonists:''' [[Leukotriene C4|Leukotriene C<sub>4</sub>]]
* [[Leukotriene D4|Leukotriene D<sub>4</sub>]]
* [[Leukotriene E4|Leukotriene E<sub>4</sub>]]

* '''Antagonists:''' [[Ablukast]]
* [[BAYu9773]]
* [[BAYu9916]]
* [[BAYx7195]]
* [[Cinalukast]]
* [[FPL-55712]]
* [[ICI-198615]]
* [[Iralukast]]
* [[LY-170680]]
* [[Masilukast]]
* [[MK-571]]
* [[Montelukast]]
* [[ONO-1078]]
* [[Pobilukast]]
* [[Pranlukast]]
* [[Ritolukast]]
* [[SKF-104353]]
* [[SR-2640]]
* [[Sulukast]]
* [[Tipelukast]]
* [[Tomelukast]]
* [[Verlukast]]
* [[Zafirlukast]]
* [[ZD-3523]]

    | group2 = {{abbrlink|CysLT<sub>2</sub>|Cysteinyl leukotriene receptor 2}}
    | list2  =
* '''Agonists:''' [[Leukotriene C4|Leukotriene C<sub>4</sub>]]
* [[Leukotriene D4|Leukotriene D<sub>4</sub>]]
* [[Leukotriene E4|Leukotriene E<sub>4</sub>]]

* '''Antagonists:''' [[BAYu9773]]
* [[BAYu9916]]

    | group3 = {{abbrlink|CysLT<sub>E</sub>|Cysteinyl leukotriene receptor E}}
    | list3  =
* '''Agonists:''' [[Leukotriene E4|Leukotriene E<sub>4</sub>]]

  }}

}}

| group2 = [[Enzyme]]<br /><small>([[Enzyme inhibitor|inhibitor]]s)</small>
| list2 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 4em;

<!--Precursor enzymes: Phospholipase A2, Phospholipase C, Diacylglycerol lipase-->

  | group1 = {{abbrlink|5-LOX|Arachidonate 5-lipoxygenase}}
  | list1 = 
* [[2-TEDC]]
* [[Baicalein]]
* [[BW-A4C]]
* [[BW-B70C]]
* [[Caffeic acid]]
* [[Cinnamyl-3,4-dihydroxy-α-cyanocinnamate|CDC]]
* [[CJ-13610]]
* [[Curcumin]]
* [[Fenleuton]]
* [[Hyperforin]]
* [[Hypericum perforatum|''Hypericum perforatum'' (St. John's Wort)]]
* [[Meclofenamic acid|Meclofenamic acid (meclofenamate)]]
* [[Minocycline]]
* [[N-Stearoyldopamine]]
* [[Timegadine]]
* [[Zileuton]]

* '''{{abbrlink|FLAP|Arachidonate 5-lipoxygenase-activating protein}} inhibitors:''' [[AM-103 (drug)|AM-103]]
* [[AM-679 (FLAP inhibitor)|AM-679]]
* [[BAYx1005]]
* [[MK-591]]
* [[MK-886]]

  | group2 = {{abbrlink|12-LOX|Arachidonate 12-lipoxygenase}}
  | list2 = 
* [[2-TEDC]]
* [[3-Methoxytropolone]]
* [[Baicalein]]
* [[Cinnamyl-3,4-dihydroxy-α-cyanocinnamate|CDC]]

  | group3 = {{abbrlink|15-LOX|Arachidonate 15-lipoxygenase}}
  | list3 = 
* [[2-TEDC]]
* [[Cinnamyl-3,4-dihydroxy-α-cyanocinnamate|CDC]]
* [[Luteolin]]
* [[PD-146176]]

  | group4 = {{abbrlink|LTA<sub>4</sub>H|Leukotriene A4 hydrolase}}
  | list4 =
* [[Acebilustat]]
* [[Captopril]]
* [[DG-051]]
* [[Fosinoprilat]]
* [[JNJ-26993135]]
* [[SA-6541]]
* [[SC-57461A]]
* [[Ubenimex|Ubenimex (bestatin)]]

  | group5 = {{abbrlink|LTB<sub>4</sub>H|Leukotriene B4 ω-hydroxylase}}
  | list5 = 
* [[17-Octadecynoic acid]]

  | group6 = {{abbrlink|LTC<sub>4</sub>S|Leukotriene C4 synthase}}
  | list6 = 
* [[Azelastine]]
* [[MK-886]]

  | group7 = {{abbrlink|LTC<sub>4</sub>H|Leukotriene C4 hydrolase}}
  | list7 = 
* [[Acivicin]]
* [[Serine-borate complex]]

  | group8 = {{abbrlink|LTD<sub>4</sub>|Leukotriene D4 hydrolase}}
  | list8 = 
* [[Cilastatin]]
* [[Ubenimex|Ubenimex (bestatin)]]

  }}

| group3 = Others
| list3 =
* '''Precursors:''' [[Linoleic acid]]
* [[gamma-Linolenic acid|γ-Linolenic acid (gamolenic acid)]]
* [[Dihomo-γ-linolenic acid]]
* [[Diglyceride|Diacylglycerol]]
* [[Arachidonic acid]]
* [[Arachidonic acid 5-hydroperoxide|5-HPETE (arachidonic acid 5-hydroperoxide)]]
* [[Leukotriene A4|Leukotriene A<sub>4</sub>]]

  | below = 
;See also
: ''[[Template:Receptor modulators|Receptor/signaling modulators]]''
: ''[[Template:Prostanoid signaling modulators|Prostanoid signaling modulators]]''
: ''[[Template:Nuclear receptor modulators|Nuclear receptor modulators]]''

}}<noinclude>
{{collapsible option}}
[[Category:Drug templates by receptor, channel, or pump]]
</noinclude>