View source for Tioconazole

{{DrugProjectFormSinglePage
|authorTag={{AJ}}
|OTC=Yes
|genericName=tioconazole
|aOrAn=a
|drugClass=antifungal ,  anti-Infective agent and imidazole
|indicationType=treatment
|indication=[[Vaginal antifungal]]
|adverseReactions=mild increase in vaginal burning, [[itching]] or irritation 
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>

* Content

<!--Adult Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=* Treats vaginal yeast infections

====DIRECTIONS====

* before using this product read the enclosed brochure and instructions on foil packet for complete directions and information
* adults and children 12 years and over:
* open the foil packet just before use and remove purple cap
* insert entire contents of applicator into the vagina at bedtime. Throw applicator away after use.

|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.

<!--Pediatric Indications and Dosage-->

<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed=* Children under 12 years of age: ask a doctor

<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.

<!--Contraindications-->
|contraindications=There is limited information regarding <i>Contraindications</i> of {{PAGENAME}} in pediatric patients.
|warnings=* For vaginal use only

=====Do not use=====

* if you have never had a vaginal yeast infection diagnosed by a doctor

=====When using this product=====

* do not use tampons, douches, spermicides, or other vaginal products. Condoms and diaphragms may be damaged and fail to prevent pregnancy or sexually transmitted disease (STDs).
* do not have vaginal intercourse
* mild increase in vaginal burning, itching or irritation may occur

=====Stop use and ask a doctor if=====

* symptoms do not get better after 3 days
* symptoms last more than 7 days
* you get a rash or hives, abdominal pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge

=====Keep out of reach of children=====
* If swallowed, get medical help or contact a Poison Control Center right away.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|drugInteractions=There is limited information regarding <i>Drug Interactions</i> of {{PAGENAME}} in the drug label.
|useInPregnancyFDA=* ask a health professional before use.

|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=* If swallowed, get medical help or contact a Poison Control Center right away.

|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.

<!--Administration and Monitoring-->
|administration=* Topical
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.

* Description

<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.

<!--Overdosage-->
|overdose=There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.

<!--Pharmacology-->

<!--Drug box 2-->
|drugBox={{one source|date=May 2014}}
{{Drugbox2
| Verifiedfields = changed
| verifiedrevid = 415485693
| IUPAC_name = (''RS'')-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1''H''-imidazole
| image = Tioconazole.png
| imagename = 1 : 1 mixture (racemate)
| drug_name = Tioconazole

<!--Clinical data-->
| tradename = Vagistat-1
| Drugs.com = {{drugs.com|monograph|tioconazole}}
| pregnancy_category =  
| legal_US=  OTC
| routes_of_administration = Topical

<!--Pharmacokinetic data-->
| bioavailability =  
| protein_bound =  
| metabolism =  
| elimination_half-life =  

<!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 65899-73-2
| ATC_prefix = D01
| ATC_suffix = AC07
| ATC_supplemental =  {{ATC|G01|AF08}}
| PubChem = 5482
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
 | DrugBank = DB01007
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 5282
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = S57Y5X1117
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00890
| ChEBI_Ref = {{ebicite|changed|EBI}} 
| ChEBI = 9604
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1200438

<!--Chemical data-->
| C=16 | H=13 | Cl=3 | N=2 | O=1 | S=1 
| molecular_weight = 387.711 g/mol
| synonyms = Thioconazole
}}
|mechAction=* 

<!--Structure-->
|structure=* butylated hydroxyanisole, magnesium aluminum silicate, white petrolatum


<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.

<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.

<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.

<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.

<!--How Supplied-->
|storage=* Store at 20° - 25°C (68° - 77°F)
|packLabel======PRINCIPAL DISPLAY PANEL=====

Compare to 1-Day active ingredient

tioconazole 1

tioconozole ointment 6.5% - vaginal antifungal

1 dose vaginal treatment

ready-to-use prefilled applicator

cures most vaginal yeast infections

1 dose treatment

NET WT 4.6g (0.16 OZ) filled applicator

[[File:TIOCONAZOLE drug lable01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]

[[File:TIOCONAZOLE drug lable02.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
|fdaPatientInfo=[[File:TIOCONAZOLE consumer info 01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
[[File:TIOCONAZOLE consumer info 02.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
[[File:TIOCONAZOLE consumer info 03.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
[[File:TIOCONAZOLE consumer info 04.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
[[File:TIOCONAZOLE consumer info 05.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
[[File:TIOCONAZOLE consumer info 06.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]

|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

<!--Brand Names-->
|brandNames=* ®
|drugShortage=
}}
{{PillImage
|fileName=No image.jpg
}}
{{LabelImage
|fileName={{PAGENAME}}11.png
}}
{{LabelImage
|fileName={{PAGENAME}}11.png
}}
<!--Pill Image-->



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<!--Category-->

[[Category:Drug]]