Bunaftine: Difference between revisions
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{{Drugbox | |||
{{ | | verifiedrevid = 447613606 | ||
| IUPAC_name = ''N''- | | IUPAC_name = ''N''-[2-(diethylamino)ethyl]-''N''-propylnaphthalene-1-carboxamide | ||
| image = Bunaftine_svg.png | | image = Bunaftine_svg.png | ||
<!--Clinical data--> | |||
| tradename = | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | |||
| pregnancy_US = <!-- A / B / C / D / X --> | |||
| pregnancy_category = | |||
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S8 --> | |||
| legal_UK = <!-- GSL / P / POM / CD --> | |||
| legal_US = <!-- OTC / Rx-only --> | |||
| legal_status = | |||
| routes_of_administration = | |||
<!--Pharmacokinetic data--> | |||
| bioavailability = | |||
| protein_bound = | |||
| metabolism = | |||
| elimination_half-life = | |||
| excretion = | |||
<!--Identifiers--> | |||
| CAS_number_Ref = {{cascite|correct|??}} | |||
| CAS_number = 32421-46-8 | | CAS_number = 32421-46-8 | ||
| ATC_prefix = C01 | | ATC_prefix = C01 | ||
| ATC_suffix = BD03 | | ATC_suffix = BD03 | ||
| PubChem = 36131 | | PubChem = 36131 | ||
| DrugBank = | | ChEMBL = 2104200 | ||
| C = 21 | H = 30 | N = 2 | O = 1 | | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | ||
| DrugBank = | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 33233 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = GH09PRQ3FU | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D07428 | |||
<!--Chemical data--> | |||
| C=21 | H=30 | N=2 | O=1 | |||
| molecular_weight = 326.476 g/mol | | molecular_weight = 326.476 g/mol | ||
| | | smiles = O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12 | ||
| | | InChI = 1/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3 | ||
| | | InChIKey = WWGZXRYELYWJBD-UHFFFAOYAK | ||
| | | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | ||
| | | StdInChI = 1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3 | ||
| | | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | ||
| StdInChIKey = WWGZXRYELYWJBD-UHFFFAOYSA-N | |||
| | |||
| | |||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | |||
{{CMG}} | {{CMG}} | ||
{{ | ==Overview== | ||
'''Bunaftine''' is an [[antiarrhythmic agent]].<ref name="pmid6876382">{{cite journal |author=Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M |title=Intropic effects of several antiarrhythmic drugs |journal=Jpn Heart J |volume=24 |issue=3 |pages=377–90 |date=May 1983 |pmid=6876382 |doi= |url=}}</ref> It is classified in [[class III antiarrhythmic|class III]].<ref name="pmid328029">{{cite journal |author=Fenici R, Marchei M, Bellocci F, Zecchi P |title=Effect of bunaphtine on right atrial repolarisation in man |journal=Br Heart J |volume=39 |issue=7 |pages=787–94 |date=July 1977 |pmid=328029 |pmc=483317 |doi= 10.1136/hrt.39.7.787|url=http://heart.bmj.com/cgi/pmidlookup?view=long&pmid=328029}}</ref> | |||
It is also spelled "bunaphtine".<ref name="pmid7436628">{{cite journal |author=Tamargo J |title=Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers |journal=Arch Int Pharmacodyn Ther |volume=246 |issue=2 |pages=224–36 |date=August 1980 |pmid=7436628 |doi= |url=}}</ref> | |||
==References== | |||
{{reflist|2}} | |||
{{Antiarrhythmic agents}} | {{Antiarrhythmic agents}} | ||
[[Category:Antiarrhythmic agents]] | [[Category:Antiarrhythmic agents]] | ||
[[Category:Drugs]] | [[Category:Cardiovascular Drugs]] | ||
[[Category:Drug]] | |||
Latest revision as of 22:24, 23 July 2014
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C21H30N2O |
| Molar mass | 326.476 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Bunaftine is an antiarrhythmic agent.[1] It is classified in class III.[2]
It is also spelled "bunaphtine".[3]
References
- ↑ Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M (May 1983). "Intropic effects of several antiarrhythmic drugs". Jpn Heart J. 24 (3): 377–90. PMID 6876382.
- ↑ Fenici R, Marchei M, Bellocci F, Zecchi P (July 1977). "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J. 39 (7): 787–94. doi:10.1136/hrt.39.7.787. PMC 483317. PMID 328029.
- ↑ Tamargo J (August 1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther. 246 (2): 224–36. PMID 7436628.