Methoxamine: Difference between revisions
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'''Methoxamine''' is an α<sub>1</sub>-[[adrenergic agonist|adrenergic receptor agonist]],<ref>{{cite book |last1=Pazdernik |first1=Thomas L. |authorlink1= |last2=Kerecsen |first2=Laszlo |editor1-first=Edward F. |editor1-last=Goljan |editor1-link= |others= |title=Pharmacology |trans_title= |url= |format=Paperback |accessdate=17 Apr 2010 |type= |edition=Second |series=Rapid Review |volume= |date= |year=2007 |month= |origyear=2003|publisher=Mosby-Elsevier |location=Philadelphia, PA |isbn=978-0-323-04550-6 |oclc= |doi= |id= |page=39 |pages= |trans_chapter= |chapter=5 |chapterurl= |quote= |ref= |bibcode= |laysummary= |laydate= |separator= |postscript= |lastauthoramp=}}</ref> similar in structure to [[phenylephrine]] and [[2,5-DMA]]. It was developed by Burroughs-Wellcome in the 1940s.<ref>US Patent 2359707 - DIMETHOXYPHENYL beta-HYDROXY ISOPROPYLAMINE</ref> The drug induces vasoconstriction of skin and [[splanchnic]] blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure. Because of its hypertensive effects, it may evoke a compensatory reflex [[bradycardia]] via the [[baroreceptors]]. | |||
== | == See Also == | ||
* [[Butaxamine]] | |||
* [[Phenylephrine]] | |||
* [[Synephrine]] | |||
== References == | |||
{{Reflist|2}} | |||
{{Stimulants}} | |||
{{Cardiac stimulants excluding cardiac glycosides}} | {{Cardiac stimulants excluding cardiac glycosides}} | ||
{{Phenethylamines}} | |||
[[Category: | [[Category:Amphetamines]] | ||
[[Category:Drugs]] | [[Category:Cardiovascular Drugs]] | ||
[[Category:Drug]] | |||
Latest revision as of 00:05, 24 July 2014
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E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
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Formula | C11H17NO3 |
Molar mass | 211.258 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Methoxamine is an α1-adrenergic receptor agonist,[1] similar in structure to phenylephrine and 2,5-DMA. It was developed by Burroughs-Wellcome in the 1940s.[2] The drug induces vasoconstriction of skin and splanchnic blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure. Because of its hypertensive effects, it may evoke a compensatory reflex bradycardia via the baroreceptors.
See Also
References
- ↑ Pazdernik, Thomas L.; Kerecsen, Laszlo (2007) [2003]. "5". In Goljan, Edward F. Pharmacology (Paperback)
|format=
requires|url=
(help). Rapid Review (Second ed.). Philadelphia, PA: Mosby-Elsevier. p. 39. ISBN 978-0-323-04550-6.|access-date=
requires|url=
(help) - ↑ US Patent 2359707 - DIMETHOXYPHENYL beta-HYDROXY ISOPROPYLAMINE
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