Bucladesine

Bucladesine

Clinical data
ATC code	C01CE04 (WHO)
Identifiers
IUPAC name sodium [(1R,2R,4R,5R)-2-[6-(butanoylamino)purin- 9-yl]-7-oxido-7-oxo-3,6,8-trioxa-7λ5- phosphabicyclo[3.3.0]oct-4-yl]methyl butanoate
CAS Number	362-74-3
PubChem CID	28177
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C18H23N5NaO8P
Molar mass	491.368 g/mol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.