Tertatolol: Difference between revisions

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Tertatolol
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	C07AA16 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (±)-1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol;
CAS Number	34784-64-0 ;
PubChem CID	36920;
IUPHAR/BPS	571;
UNII	9ZO341YQXP;
KEGG	D07182 ;
ChEMBL	ChEMBL434200 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C16H25NO2S
Molar mass	295.44 g/mol
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VisualWikitext

Latest revision as of 02:47, 25 July 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.^[1]

Tertatolol has also been shown to act as a 5-HT_1A receptor antagonist, similarly to pindolol.^[2]^[3]

External Links

Servier official website

References

↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.
↑ Jolas T, Haj-Dahmane S, Lanfumey L; et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology. 347 (5): 453–63. PMID 7686633.
↑ Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8.

[isbn3-88763-075-0-1] Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.

[pmid7686633-2] Jolas T, Haj-Dahmane S, Lanfumey L; et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology. 347 (5): 453–63. PMID 7686633.

[isbn0-444-82041-8-3] Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-{{Drugbox|
+{{Drugbox
-|IUPAC_name = 1-(''tert''-Butylamino)-3-thiochroman-8-yloxypropan-2-ol
+| Verifiedfields = changed
-| image = Tertatolol.png
+| Watchedfields = changed
+| verifiedrevid = 408926545
+| IUPAC_name = (±)-1-(''tert''-butylamino)-3-(3,4-dihydro-2''H''-thiochromen-8-yloxy)propan-2-ol
+| drug_name = Tertatolol
+<!--Clinical data-->
+| tradename =
+| Drugs.com = {{drugs.com|international|tertatolol}}
+| pregnancy_category =
+| legal_status = Rx-only
+| routes_of_administration = Oral
+<!--Pharmacokinetic data-->
+| bioavailability =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
 | CAS_number = 34784-64-0
 | ATC_prefix = C07
-| ATC_suffix = AA17
+| ATC_suffix = AA16
-| ATC_supplemental =
+| PubChem = 36920
-| PubChem= 36920
+| IUPHAR_ligand = 571
-| DrugBank=
+| UNII_Ref = {{fdacite|changed|FDA}}
-| C = 16 | H = 25 | N = 1 | O = 2 | S=1
+| UNII = 9ZO341YQXP
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D07182
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 434200
+<!--Chemical data-->
+| C=16 | H=25 | N=1 | O=2 | S=1
 | molecular_weight = 295.44 g/mol
-| bioavailability=
-| metabolism =
-| elimination_half-life=
-| excretion =
-| pregnancy_category =
-| legal_status =
-| routes_of_administration=
 }}
+__NOTOC__
+{{SI}}
+{{CMG}}
-{{CMG}}
+==Overview==
+'''Tertatolol''' ('''Artex''', '''Artexal''', '''Prenalex''') is a [[medication]] in the class of [[beta blocker]]s, used in the treatment of [[hypertension|high blood pressure]]. It was discovered by the French pharmaceutical company [[Servier]] and is marketed in Europe.<ref name="isbn3-88763-075-0">{{cite book | author = Swiss Pharmaceutical Society | title = Index Nominum 2000: International Drug Directory (Book with CD-ROM) | publisher = Medpharm Scientific Publishers | location = Boca Raton | year = 2000 | pages = | isbn = 3-88763-075-0 | oclc = | doi = | url = http://books.google.com/books?id=5GpcTQD_L2oC&lpg=PA1002&pg=PA1002#v=onepage&q=&f=false}}</ref>
+Tertatolol has also been shown to act as a [[5-HT1A receptor|5-HT<sub>1A</sub> receptor]] [[receptor antagonist|antagonist]], similarly to [[pindolol]].<ref name="pmid7686633">{{cite journal | author = Jolas T, Haj-Dahmane S, Lanfumey L, ''et al.'' | title = (-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | volume = 347 | issue = 5 | pages = 453–63 |date=May 1993 | pmid = 7686633 | doi = | url = }}</ref><ref name="isbn0-444-82041-8">{{cite book | author = Soudijn, W.; Olivier, Berend; Wijngaarden, I. van | title = Serotonin receptors and their ligands | publisher = Elsevier | location = Amsterdam | year = 1997 | pages = | isbn = 0-444-82041-8 | oclc = | doi = | url = http://books.google.com/books?id=lfo0hGqIex0C&lpg=PA37&pg=PA37#v=onepage&q=&f=false}}</ref>
+==See Also==
-{{EH}}
+* [[Beta blocker]]
-'''Tertatolol''' is a [[medication]] in the class of [[beta blocker]]s, used in the treatment of [[hypertension|high blood pressure]]. It was discovered by the French pharmaceutical company [[Servier]].
+==External Links==
-==External links==
+* [http://www.servier.com/index.asp Servier official website]
-*[http://www.servier.com/index.asp Servier official website]
-[[Category:Beta blockers]]
+==References==
+{{reflist|2}}
 {{Beta blockers}}
-{{WH}}
+[[Category:Cardiovascular Drugs]]
-{{WS}}
+[[Category:Drug]]
+[[Category:Beta blockers]]

v t e Beta blockers (C07)
Non-selective β antagonists	Metipranolol • Nadolol • Oxprenolol • Penbutolol • Pindolol • Propranolol • Tertatolol • Timolol • Sotalol
β₁ antagonists (cardioselective)	Atenolol • Acebutolol • Celiprolol • Betaxolol • Bisoprolol • Esmolol • Metoprolol • Nebivolol
Mixed α₁/β antagonists	Carvedilol • Labetalol

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	C07AA16 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (±)-1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
CAS Number	34784-64-0^Y
PubChem CID	36920
IUPHAR/BPS	571
UNII	9ZO341YQXP
KEGG	D07182^Y
ChEMBL	ChEMBL434200^N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₆H₂₅NO₂S
Molar mass	295.44 g/mol
^NY (what is this?) (verify)

Tertatolol: Difference between revisions

Latest revision as of 02:47, 25 July 2014

Overview

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References

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