Tertatolol: Difference between revisions
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| verifiedrevid = 408926545 | | verifiedrevid = 408926545 | ||
| IUPAC_name = (±)-1-(''tert''-butylamino)-3-(3,4-dihydro-2''H''-thiochromen-8-yloxy)propan-2-ol | | IUPAC_name = (±)-1-(''tert''-butylamino)-3-(3,4-dihydro-2''H''-thiochromen-8-yloxy)propan-2-ol | ||
| drug_name = Tertatolol | | drug_name = Tertatolol | ||
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==Overview== | ==Overview== | ||
'''Tertatolol''' ('''Artex''', '''Artexal''', '''Prenalex''') is a [[medication]] in the class of [[beta blocker]]s, used in the treatment of [[hypertension|high blood pressure]]. It was discovered by the French pharmaceutical company [[Servier]] and is marketed in | '''Tertatolol''' ('''Artex''', '''Artexal''', '''Prenalex''') is a [[medication]] in the class of [[beta blocker]]s, used in the treatment of [[hypertension|high blood pressure]]. It was discovered by the French pharmaceutical company [[Servier]] and is marketed in Europe.<ref name="isbn3-88763-075-0">{{cite book | author = Swiss Pharmaceutical Society | title = Index Nominum 2000: International Drug Directory (Book with CD-ROM) | publisher = Medpharm Scientific Publishers | location = Boca Raton | year = 2000 | pages = | isbn = 3-88763-075-0 | oclc = | doi = | url = http://books.google.com/books?id=5GpcTQD_L2oC&lpg=PA1002&pg=PA1002#v=onepage&q=&f=false}}</ref> | ||
Tertatolol has also been shown to act as a [[5-HT1A receptor|5-HT<sub>1A</sub> receptor]] [[receptor antagonist|antagonist]], similarly to [[pindolol]].<ref name="pmid7686633">{{cite journal | author = Jolas T, Haj-Dahmane S, Lanfumey L, ''et al.'' | title = (-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | volume = 347 | issue = 5 | pages = 453–63 |date=May 1993 | pmid = 7686633 | doi = | url = }}</ref><ref name="isbn0-444-82041-8">{{cite book | author = Soudijn, W.; Olivier, Berend; Wijngaarden, I. van | title = Serotonin receptors and their ligands | publisher = Elsevier | location = Amsterdam | year = 1997 | pages = | isbn = 0-444-82041-8 | oclc = | doi = | url = http://books.google.com/books?id=lfo0hGqIex0C&lpg=PA37&pg=PA37#v=onepage&q=&f=false}}</ref> | Tertatolol has also been shown to act as a [[5-HT1A receptor|5-HT<sub>1A</sub> receptor]] [[receptor antagonist|antagonist]], similarly to [[pindolol]].<ref name="pmid7686633">{{cite journal | author = Jolas T, Haj-Dahmane S, Lanfumey L, ''et al.'' | title = (-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | volume = 347 | issue = 5 | pages = 453–63 |date=May 1993 | pmid = 7686633 | doi = | url = }}</ref><ref name="isbn0-444-82041-8">{{cite book | author = Soudijn, W.; Olivier, Berend; Wijngaarden, I. van | title = Serotonin receptors and their ligands | publisher = Elsevier | location = Amsterdam | year = 1997 | pages = | isbn = 0-444-82041-8 | oclc = | doi = | url = http://books.google.com/books?id=lfo0hGqIex0C&lpg=PA37&pg=PA37#v=onepage&q=&f=false}}</ref> | ||
==See | ==See Also== | ||
* [[Beta blocker]] | * [[Beta blocker]] | ||
== | ==External Links== | ||
* [http://www.servier.com/index.asp Servier official website] | |||
== | ==References== | ||
{{reflist|2}} | |||
{{Beta blockers}} | {{Beta blockers}} | ||
[[Category:Cardiovascular Drugs]] | |||
[[Category:Drug]] | |||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
Latest revision as of 02:47, 25 July 2014
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| Routes of administration | Oral |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C16H25NO2S |
| Molar mass | 295.44 g/mol |
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WikiDoc Resources for Tertatolol |
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Ongoing Trials on Tertatolol at Clinical Trials.gov Clinical Trials on Tertatolol at Google
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US National Guidelines Clearinghouse on Tertatolol
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Patient resources on Tertatolol Discussion groups on Tertatolol Patient Handouts on Tertatolol Directions to Hospitals Treating Tertatolol Risk calculators and risk factors for Tertatolol
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.[1]
Tertatolol has also been shown to act as a 5-HT1A receptor antagonist, similarly to pindolol.[2][3]
See Also
External Links
References
- ↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.
- ↑ Jolas T, Haj-Dahmane S, Lanfumey L; et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology. 347 (5): 453–63. PMID 7686633.
- ↑ Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8.
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