Primary cutaneous amyloidosis: Difference between revisions
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{{ | {{Infobox disease | ||
| Name = Primary cutaneous amyloidosis | |||
| Image = Macular amyloidosis.jpg | |||
| Caption = Macular amyloidosis, located on the right lumbar region of the back | |||
| DiseasesDB = 29871 | |||
| ICD10 = | |||
| ICD9 = {{ICD9|277.3}} | |||
| ICDO = | |||
| OMIM = 105250 | |||
| MedlinePlus = | |||
| eMedicineSubj = | |||
| eMedicineTopic = | |||
| MeshID = | |||
}} | }} | ||
{{ | __NOTOC__ | ||
{{CMG}};{{AE}} {{KS}} | |||
==Overview== | |||
'''Primary cutaneous amyloidosis''' is a form of [[amyloidosis]] associated with [[oncostatin M receptor]].<ref name="urlAmyloid">{{cite web |url=http://neuromuscular.wustl.edu/nother/amyloid.htm |title=Amyloid |work= |accessdate=}}</ref><ref name="pmid18179886">{{cite journal |author=Arita K, South AP, Hans-Filho G, ''et al.'' |title=Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis |journal=Am. J. Hum. Genet. |volume=82 |issue=1 |pages=73–80 |date=January 2008 |pmid=18179886 |doi=10.1016/j.ajhg.2007.09.002 |url= |pmc=2253984}}</ref> This type of amyloidosis has been divided into the following types:<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|520}} | |||
{{ | * '''Macular amyloidosis''' is a cutaneous condition characterized by itchy, brown, rippled [[macule]]s usually located on the interscapular region of the back.<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|521}} Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum. <ref name="Craig">[http://dermatology-s10.cdlib.org/125/UCDcases/amlyoid/craig.html Lichen amyloidosis of the auricular concha] Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology</ref> | ||
* '''Lichen amyloidosis''' is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid [[papule]]s, typically appearing bilaterally on the shins.<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|521}} | |||
* '''Nodular amyloidosis''' is a rare cutaneous condition characterized by nodules that involve the acral areas.<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|521}} | |||
==Diagnosis== | |||
===Physical Examination=== | |||
====Skin==== | |||
=====Macular Amyloidosis===== | |||
======Lower Extremity====== | |||
<gallery> | |||
Image:Macular amyloidosis01.jpg|Macular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
</gallery> | |||
======Trunk====== | |||
<gallery> | |||
Image:Macular amyloidosis02.jpg|Macular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Macular amyloidosis03.jpg|Macular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Macular amyloidosis04.jpg|Macular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Macular amyloidosis04.jpg|Macular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
</gallery> | |||
=====Nodular Amyloidosis===== | |||
======Face====== | |||
<gallery> | |||
Image:Nodular amyloidosis01.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis02.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis03.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis04.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis05.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis06.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis07.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis08.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis09.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis10.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis11.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis12.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis13.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
Image:Nodular amyloidosis14.jpg|Nodular amyloidosis. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite | |||
</gallery> | |||
=====Lichen Amyloidosus===== | |||
======Extremity====== | |||
<gallery> | |||
Image:Lichen amyloidosus01.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus02.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus03.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus04.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus05.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus06.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus07.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus08.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus09.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus10.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus11.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus12.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus13.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus14.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus15.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus16.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | |||
======Trunk====== | |||
<gallery> | |||
Image:Lichen amyloidosus17.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus18.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Lichen amyloidosus19.jpg|.Lichen amyloidosus <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | |||
== See also == | |||
* [[Amyloidosis]] | |||
* [[List of cutaneous conditions]] | |||
== References == | |||
{{reflist}} | |||
{{Amyloidosis}} | |||
[[Category:Skin conditions resulting from errors in metabolism]] | |||
==References== | ==References== |
Latest revision as of 13:31, 10 September 2014
Primary cutaneous amyloidosis | |
Classification and external resources | |
File:Macular amyloidosis.jpg | |
---|---|
Macular amyloidosis, located on the right lumbar region of the back | |
ICD-9 | 277.3 |
OMIM | 105250 |
DiseasesDB | 29871 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
Overview
Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[1][2] This type of amyloidosis has been divided into the following types:[3]:520
- Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[3]:521 Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum. [4]
- Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[3]:521
- Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.[3]:521
Diagnosis
Physical Examination
Skin
Macular Amyloidosis
Lower Extremity
-
Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
Trunk
-
Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Macular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
Nodular Amyloidosis
Face
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
-
Nodular amyloidosis. Adapted from Dermatology Atlas.<ref name="Dermatology Atlas">{{Cite
Lichen Amyloidosus
Extremity
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
Trunk
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
-
.Lichen amyloidosus Adapted from Dermatology Atlas.[5]
See also
References
- ↑ "Amyloid".
- ↑ Arita K, South AP, Hans-Filho G; et al. (January 2008). "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis". Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.
- ↑ 3.0 3.1 3.2 3.3 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ↑ Lichen amyloidosis of the auricular concha Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 "Dermatology Atlas".
Amyloidosis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Primary cutaneous amyloidosis On the Web |
American Roentgen Ray Society Images of Primary cutaneous amyloidosis |
Risk calculators and risk factors for Primary cutaneous amyloidosis |
References
Amyloidosis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Primary cutaneous amyloidosis On the Web |
American Roentgen Ray Society Images of Primary cutaneous amyloidosis |
Risk calculators and risk factors for Primary cutaneous amyloidosis |