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| __NOTOC__
| | #Redirect [[High density lipoprotein classification]] |
| {{High density lipoprotein}}
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| {{CMG}} ;{{AE}} {{MM}}
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| ==Overview==
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| Based on the physiological action of [[High density lipoprotein]] particles by removing the fats from cells and deliver it to liver to be excreted, many studies admitted the inverse relation between [[HDL]] level and the risk of cardiovascular diseases.
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| ==Definition==
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| Many large studies and clinical trials have been done to prove the inverse relation between HDL and the risk of cardiovascular diseases,<ref name="pmid10662743">{{cite journal| author=Gotto AM, Whitney E, Stein EA, Shapiro DR, Clearfield M, Weis S et al.| title=Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). | journal=Circulation | year= 2000 | volume= 101 | issue= 5 | pages= 477-84 | pmid=10662743 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10662743 }} </ref><ref name="pmid19903920">{{cite journal| author=Emerging Risk Factors Collaboration. Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK et al.| title=Major lipids, apolipoproteins, and risk of vascular disease. | journal=JAMA | year= 2009 | volume= 302 | issue= 18 | pages= 1993-2000 | pmid=19903920 | doi=10.1001/jama.2009.1619 | pmc=PMC3284229 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19903920 }} [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20157124 Review in: Ann Intern Med. 2010 Feb 16;152(4):JC-212] </ref> and the fact that more increase in HDL level improves the cardiovascular health.<ref>{{cite web | url= http://eurheartjsupp.oxfordjournals.org/content/8/suppl_F/F4.full | last=Sirtori | first=Cesare R. | title=HDL and the progression of atherosclerosis: new insights | date=October 2006 | work=European Heart Journal Supplements}}</ref> The serum HDL level Goals for Patients at Risk of cardiovascular disease is recommended to be as high as possible, but at least ≥40 mg/dL in both men and women. Many debate about the serum level at which the risk of cardiovascular disease occurrence decline, an HDL value of ≥60 mg/dL is considered protective against heart disease according to latest guidelines.
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| ===Guideline Resource===
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| https://www.aace.com/files/lipid-guidelines.pdf
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| ==References==
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| {{Reflist|2}}
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| {{Lipopedia}}
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| [[Category:Lipopedia]]
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| [[Category:Lipid disorders]]
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| [[Category:Cardiology]]
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| [[Category:Lipoproteins]]
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