High HDL causes: Difference between revisions

	High Density Lipoprotein Microchapters
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Latest revision as of 18:11, 9 October 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The causes of elevated high-density lipoprotein (HDL) include life-style measures such as aerobic exercises, weight loss, smoking cessation, consumption of dietary fibers, as well as medications (e.g., fibrates, niacin, statins). Genetic factors which affect the catabolism of HDL have also been implicated in high HDL serum concentrations, including cholesteryl ester transfer protein (CETP) deficiency and familial hyperalphalipoproteinemia or hepatic lipase deficiency.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

High HDL does not have any life-threatening cause.

Common Causes

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	Benign symmetrical lipomatosis
Dermatologic	No underlying causes
Drug Effect	Anacetrapib, apoA-1 Milano, cannabis, CER-001, CSL-112, dalcetrapib,doxazosin, estrogen, fibrate, lovaza, moderate alcohol consumption, niacin, prazosin, statins, torcetrapib
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Liver cirrhosis, primary biliary cirrhosis
Genetic	Benign symmetrical lipomatosis, cholesteryl ester transfer protein (CETP) deficiency, familial hyperalphalipoproteinemia or hepatic lipase deficiency
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	Caprylic acid, decanoic acid, dietary fiber, hexanoic acid , lauric acid, magnesium, omega-3 fatty acid, unsaturated fat
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	Anorexia nervosa
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Primary biliary cirrhosis
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Aerobic exercise, excessive weight loss, smoking cessation

Causes by Alphabetical Order

References

Template:WikiDoc Sources

@@ Line 4: / Line 4: @@
 ==Overview==
+The causes of elevated high-density lipoprotein (HDL) include life-style measures such as [[aerobic exercise]]s, [[weight loss]], [[smoking cessation]], consumption of [[dietary fiber]]s, as well as medications (e.g., [[fibrates]], [[niacin]], [[statins]]). [[Genetic]] factors which affect the catabolism of HDL have also been implicated in high HDL serum concentrations, including [[Cholesterylester transfer protein|cholesteryl ester transfer protein (CETP) deficiency]] and [[Hepatic lipase|familial hyperalphalipoproteinemia or hepatic lipase deficiency]].
 ==Causes==
@@ Line 9: / Line 10: @@
 ===Life Threatening Causes===
 Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
+High HDL does not have any life-threatening cause.
 ===Common Causes===
+{{col-begin|width=80%}}
+{{col-break|width=33%}}
+*[[Aerobic exercise]]
+*[[Anorexia nervosa]]
+*[[Cannabis]]
+*[[Doxazosin]]
+*[[Estrogen]]
+*[[Weight loss|Excessive weight loss]]
+*[[Fibrates]]
+*[[Liver cirrhosis]]
+*[[Lovaza]]
+{{col-break|width=33%}}
+*[[Magnesium]]
+*[[Alcohol and cardiovascular disease#Possible Mechanisms of Benefits|Moderate alcohol consumption]]
+*[[Niacin]]
+*[[Omega-3 fatty acid]]
+*[[Prazosin]]
+*[[Smoking cessation]]
+*[[Statins]]
+*[[Unsaturated fat]]
+{{col-end}}
 ===Causes by Organ System===
@@ Line 22: / Line 46: @@
 |-bgcolor="LightSteelBlue"
 | '''Dental'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Lipoma|Benign symmetrical lipomatosis]]
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 30: / Line 54: @@
 |-bgcolor="LightSteelBlue"
 | '''Drug Effect'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"|  [[Anacetrapib]], [[apoA-1 Milano]], [[cannabis]], [[CHI-SQUARE Study|CER-001]], [[CSL-112 Trial - Phase 1|CSL-112]], [[dalcetrapib]],[[doxazosin]], [[estrogen]], [[fibrate]], [[lovaza]], [[Alcohol|moderate alcohol consumption]], [[niacin]], [[prazosin]], [[statins]], [[torcetrapib]]
-|-
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 37: / Line 60: @@
 |bgcolor="Beige"| No underlying causes
 |-
 |-bgcolor="LightSteelBlue"
 | '''Ear Nose Throat'''
@@ Line 52: / Line 74: @@
 |-bgcolor="LightSteelBlue"
 | '''Gastroenterologic'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Liver cirrhosis]], [[primary biliary cirrhosis]]
 |-
 |-bgcolor="LightSteelBlue"
 | '''Genetic'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Lipoma|Benign symmetrical lipomatosis]], [[Cholesterylester transfer protein|cholesteryl ester transfer protein (CETP) deficiency]], [[Hepatic lipase|familial hyperalphalipoproteinemia or hepatic lipase deficiency]]
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 80: / Line 102: @@
 |-bgcolor="LightSteelBlue"
 | '''Nutritional/Metabolic'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"|  [[Caprylic acid]], [[decanoic acid]], [[dietary fiber]], [[hexanoic acid ]], [[lauric acid]], [[magnesium]], [[omega-3 fatty acid]], [[unsaturated fat]]
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 100: / Line 122: @@
 |-bgcolor="LightSteelBlue"
 | '''Psychiatric'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Anorexia nervosa]]
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 112: / Line 134: @@
 |-bgcolor="LightSteelBlue"
 | '''Rheumatology/Immunology/Allergy'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Primary biliary cirrhosis]]
 |-
 |-bgcolor="LightSteelBlue"
@@ Line 128: / Line 150: @@
 |-bgcolor="LightSteelBlue"
 | '''Miscellaneous'''
-|bgcolor="Beige"| No underlying causes
+|bgcolor="Beige"| [[Aerobic exercise]], [[Weight loss|excessive weight loss]], [[smoking cessation]]
 |-
 |}
@@ Line 135: / Line 157: @@
 {{col-begin|width=80%}}
 {{col-break|width=33%}}
+*[[Aerobic exercise]]
+*[[Anacetrapib]]
+*[[Anorexia nervosa]]
+*[[ApoA-1 Milano]]
+*[[Lipoma|Benign symmetrical lipomatosis]]
+*[[Cannabis]]
+*[[Caprylic acid]]
+*[[CHI-SQUARE Study|CER-001]]
+*[[Cholesterylester transfer protein|Cholesteryl ester transfer protein (CETP) deficiency]]
+*[[CSL-112 Trial - Phase 1|CSL-112]]
+*[[Dalcetrapib]]
+*[[Decanoic acid]]
+*[[Dietary fiber]]
+*[[Doxazosin]]
+*[[Estrogen]]
+*[[Weight loss|Excessive weight loss]]
+{{col-break|width=33%}}
+*[[Hepatic lipase|Familial hyperalphalipoproteinemia or hepatic lipase deficiency]]
+*[[Fibrates]]
+*[[Hexanoic acid]]
+*[[Lauric acid]]
+*[[Liver cirrhosis]]
+*[[Lovaza]]
+*[[Magnesium]]
+*[[Alcohol and cardiovascular disease#Possible Mechanisms of Benefits|Moderate alcohol consumption]]
+*[[Niacin]]
+*[[Omega-3 fatty acid]]
+*[[Prazosin]]
+*[[Primary biliary cirrhosis]]
+*[[Smoking cessation]]
+*[[Statins]]
+*[[Torcetrapib]]
+*[[Unsaturated fat]]
 {{col-end}}
@@ Line 146: / Line 201: @@
 [[Category:Cardiology]]
 [[Category:Lipoproteins]]
+[[Category:HDLpedia]]
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}

v t e Lipopedia
Basic Science	Cholesterol • Triglyceride Lipoprotein metabolism and transport Lipoprotein: Chylomicron • Chylomicron remnant • HDL • IDL • LDL • Lipoprotein(a) • VLDL • Lipoprotein-X Apolipoprotein: APOA (1, 2, 4, 5) • APOB ( Apolipoprotein B-48, Apolipoprotein B-100) • APOC (1, 2, 3, 4) • APOD • APOE • APOH • APOJ • APOL • APOM • Apo(a) Lipoprotein receptor: LDL receptor • Soluble low density lipoprotein receptor-related protein (sLRP) • Apolipoprotein E Receptor 2 • Scavenger receptor • Scavenger receptor A • Scavenger receptor B • VLDL receptor Lipoprotein enzymes: Lipoprotein lipase • Lipoprotein-associated phospholipase A2 (Lp-PLA2) • Cholesterylester transfer protein ( Acetyl-CoA C-acyltransferase, Lecithin-cholesterol acyltransferase) • Microsomal triglyceride transfer protein • ABCA1 Genes: Low density lipoprotein receptor gene family • Microsomal triglyceride transfer protein • ABCA1
Lipoprotein Disorders	Lipoprotein disorders Primary lipoprotein disorders: Familial hyperchylomicronemia (Type I) • Familial hypercholesterolemia (Type IIA) • Familial combined hyperlipidemia (Type IIB) • Dysbetalipoproteinemia (Type III) • Primary hypertriglyceridemia (Type IV) • Mixed hyperlipoproteinemia (Type V) Secondary lipoprotein disorders
Abnormal Laboratory Lipid Profile	Low chylomicron • Low chylomicron remnant • Low HDL • Low IDL • Low LDL • Low lipoprotein(a) • Low VLDL High chylomicron • High chylomicron remnant • High HDL • High IDL • High LDL • High Lipoprotein(a) • High VLDL