Low density lipoprotein screening: Difference between revisions
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==Overview== | ==Overview== | ||
According to the [[United states preventive services task force recommendations scheme|United States Preventive Services Task Force (USPSTF)]], screening for dyslipidemia, which includes high LDL-cholesterol (LDL-c), is indicated among men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), men 20 to 35 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]), women 45 years and older in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), and women 20 to 45 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref> There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref> | |||
==Screening== | ==Screening== | ||
===Screening in Adults=== | ===Screening Indications=== | ||
Screening for [[dyslipidemia]], including high LDL, is indicated among the following:<ref> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/ | ====Screening in Adults==== | ||
Screening for [[dyslipidemia]], including high LDL, depends on the gender, age, and the risk for [[coronary heart disease]]. Screening for [[dyslipidemia]] is indicated among the following:<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref> | |||
===Screening in Children=== | * Men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]) | ||
There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age.<ref> | * Men 20 to 35 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]) | ||
U.S. Preventive Services Task Force. Screening for | * Women 45 years and older in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]) | ||
* Women 20 to 45 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]) | |||
====Screening in Children==== | |||
There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref> | |||
===Screening Components=== | |||
Screening for [[dyslipidemia]] includes:<ref name="pmid22507559">{{cite journal| author=Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW et al.| title=American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis: executive summary. | journal=Endocr Pract | year= 2012 | volume= 18 | issue= 2 | pages= 269-93 | pmid=22507559 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22507559 }} </ref> | |||
* Identification of risk factors for [[coronary artery disease]] | |||
* Estimation of the 10-year risk of [[cardiovascular disease]] | |||
* Measurement of fasting lipid panel (total [[cholesterol]], [[LDL]], [[HDL]], [[triglycerides]]) | |||
==References== | ==References== | ||
Latest revision as of 19:58, 9 October 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [3]
Overview
According to the United States Preventive Services Task Force (USPSTF), screening for dyslipidemia, which includes high LDL-cholesterol (LDL-c), is indicated among men 35 years and older (Grade: A Recommendation), men 20 to 35 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation), women 45 years and older in case of an elevated risk for coronary heart disease (Grade: A Recommendation), and women 20 to 45 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation).[1] There is insufficient evidence to recommend for or against screening for dyslipidemia among infants, children, adolescents, or young adults less than 20 years of age (Grade: I statement).[1]
Screening
Screening Indications
Screening in Adults
Screening for dyslipidemia, including high LDL, depends on the gender, age, and the risk for coronary heart disease. Screening for dyslipidemia is indicated among the following:[1]
- Men 35 years and older (Grade: A Recommendation)
- Men 20 to 35 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation)
- Women 45 years and older in case of an elevated risk for coronary heart disease (Grade: A Recommendation)
- Women 20 to 45 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation)
Screening in Children
There is insufficient evidence to recommend for or against screening for dyslipidemia among infants, children, adolescents, or young adults less than 20 years of age (Grade: I statement).[1]
Screening Components
Screening for dyslipidemia includes:[2]
- Identification of risk factors for coronary artery disease
- Estimation of the 10-year risk of cardiovascular disease
- Measurement of fasting lipid panel (total cholesterol, LDL, HDL, triglycerides)
References
- ↑ 1.0 1.1 1.2 1.3 Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [1]
- ↑ Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW; et al. (2012). "American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis: executive summary". Endocr Pract. 18 (2): 269–93. PMID 22507559.