Low density lipoprotein screening: Difference between revisions

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==Overview==
==Overview==
According to the [[United states preventive services task force recommendations scheme|United States Preventive Services Task Force (USPSTF)]], screening for high LDL-cholesterol (LDL-c), is indicated among men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), men age 20 to 35 years in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]), women age 45 years and older for in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), and women age 20 to 45 years in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]).<ref> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/uspstf/uspschol.htm] </ref>  There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref> U.S. Preventive Services Task Force. Screening for Lipid Disorders in Children: Recommendation Statement. July 2007.[http://www.uspreventiveservicestaskforce.org/uspstf07/chlipid/chlipidrs.htm]</ref>
According to the [[United states preventive services task force recommendations scheme|United States Preventive Services Task Force (USPSTF)]], screening for dyslipidemia, which includes high LDL-cholesterol (LDL-c), is indicated among men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), men 20 to 35 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]), women 45 years and older in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]]), and women 20 to 45 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref>  There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref>


==Screening==
==Screening==
===Screening Indications===
===Screening Indications===
====Screening in Adults====
====Screening in Adults====
Screening for [[dyslipidemia]], including high LDL, depends on the gender, age, and the risk for [[coronary heart disease]].  Screening for high HDL is indicated among the following:<ref> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/uspstf/uspschol.htm] </ref>
Screening for [[dyslipidemia]], including high LDL, depends on the gender, age, and the risk for [[coronary heart disease]].  Screening for [[dyslipidemia]] is indicated among the following:<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref>


* Men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]])
* Men 35 years and older ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]])
* Men 20 to 35 years in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]])
* Men 20 to 35 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]])
* Women 45 years and older for in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]])
* Women 45 years and older in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: A Recommendation]])
* Women 20 to 45 years in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]])
* Women 20 to 45 years old in case of an elevated risk for [[coronary heart disease]] ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: B Recommendation]])


====Screening in Children====
====Screening in Children====
There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref>
There is insufficient evidence to recommend for or against screening for [[dyslipidemia]] among infants, children, adolescents, or young adults less than 20 years of age ([[United states preventive services task force recommendations scheme#USPSTF Grade Definitions|Grade: I statement]]).<ref name=USPSTF> Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [http://www.uspreventiveservicestaskforce.org/Page/Topic/recommendation-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening] </ref>
U.S. Preventive Services Task Force. Screening for Lipid Disorders in Children: Recommendation Statement. July 2007.[http://www.uspreventiveservicestaskforce.org/uspstf07/chlipid/chlipidrs.htm]</ref>


===Screening Components===
===Screening Components===
Screening for [[high LDL]] includes:<ref name="pmid22507559">{{cite journal| author=Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW et al.| title=American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis: executive summary. | journal=Endocr Pract | year= 2012 | volume= 18 | issue= 2 | pages= 269-93 | pmid=22507559 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22507559  }} </ref>
Screening for [[dyslipidemia]] includes:<ref name="pmid22507559">{{cite journal| author=Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW et al.| title=American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis: executive summary. | journal=Endocr Pract | year= 2012 | volume= 18 | issue= 2 | pages= 269-93 | pmid=22507559 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22507559  }} </ref>
* Identification of risk factors for [[coronary artery disease]]
* Identification of risk factors for [[coronary artery disease]]
* Estimation of the 10-year risk of [[cardiovascular disease]]
* Estimation of the 10-year risk of [[cardiovascular disease]]

Latest revision as of 19:58, 9 October 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [3]

Overview

According to the United States Preventive Services Task Force (USPSTF), screening for dyslipidemia, which includes high LDL-cholesterol (LDL-c), is indicated among men 35 years and older (Grade: A Recommendation), men 20 to 35 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation), women 45 years and older in case of an elevated risk for coronary heart disease (Grade: A Recommendation), and women 20 to 45 years old in case of an elevated risk for coronary heart disease (Grade: B Recommendation).[1] There is insufficient evidence to recommend for or against screening for dyslipidemia among infants, children, adolescents, or young adults less than 20 years of age (Grade: I statement).[1]

Screening

Screening Indications

Screening in Adults

Screening for dyslipidemia, including high LDL, depends on the gender, age, and the risk for coronary heart disease. Screening for dyslipidemia is indicated among the following:[1]

Screening in Children

There is insufficient evidence to recommend for or against screening for dyslipidemia among infants, children, adolescents, or young adults less than 20 years of age (Grade: I statement).[1]

Screening Components

Screening for dyslipidemia includes:[2]

References

  1. 1.0 1.1 1.2 1.3 Screening for Lipid Disorders in Adults, Topic Page. U.S. Preventive Services Task Force. [1]
  2. Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW; et al. (2012). "American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis: executive summary". Endocr Pract. 18 (2): 269–93. PMID 22507559.


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