Sleep-related hypoventilation: Difference between revisions
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==Overview== | ==Overview== | ||
Sleep-related hypoventilation is characterized by decreased respiration | Sleep-related hypoventilation is characterized by multiple episodes of decreased respiration with polysomnography evidence of high CO<sub>2</sub> levels and low oxygen saturation during these episodes. Sleep-related hypoventilation may be idiopathic, congenital or associated with another medical condition.<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558}}</ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
| Line 33: | Line 33: | ||
:* Toxic or metabolic myopathies | :* Toxic or metabolic myopathies | ||
:* Postpolio syndrome | :* Postpolio syndrome | ||
:* Charcot-Marie-Tooth syndrome | :* Charcot-Marie-Tooth syndrome<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558}}</ref> | ||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
===DSM-V Diagnostic Criteria for Sleep | ===DSM-V Diagnostic Criteria for Sleep-related Hypoventilation<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558 }}</ref>=== | ||
{{cquote| | {{cquote| | ||
* A. [[Polysomnograpy]] demonstrates episodes of decreased respiration associated with elevated CO2 levels. | * A. [[Polysomnograpy]] demonstrates episodes of decreased respiration associated with elevated CO2 levels. | ||
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Specify whether: | Specify whether: | ||
: '''Idiopathic | : '''Idiopathic hypoventilation:''' This subtype is not attributable to any readily identified condition. | ||
: '''Congenital central alveolar hypoventilation:''' This subtype is a rare congenital disorder in which the individual typically presents in the perinatal period with shallow breathing, or [[cyanosis]] and apnea during sleep. | : '''Congenital central alveolar hypoventilation:''' This subtype is a rare congenital disorder in which the individual typically presents in the perinatal period with shallow breathing, or [[cyanosis]] and apnea during sleep. | ||
Latest revision as of 21:09, 13 November 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]
Overview
Sleep-related hypoventilation is characterized by multiple episodes of decreased respiration with polysomnography evidence of high CO2 levels and low oxygen saturation during these episodes. Sleep-related hypoventilation may be idiopathic, congenital or associated with another medical condition.[1]
Differential Diagnosis
- Lung diseases
- Skeletal malformations
- Neuromuscular disorders
- Sleep-related hypoxemia
- Obstructive sleep apnea hypopnea
- Central sleep apnea[1]
Risk Factors
- Central nervous system depressants intake (e.g. benzodiazepines, opioid, alcohol)
- Hypothiroidism
- Neuromuscular or chest wall disorder
- Pulmonary disorder[1]
Natural History, Complications and Prognosis
Prognosis
Poor prognostic factors include:
- Central nervous system depressants intake (e.g. benzodiazepines, opioid, alcohol)
- Hypothiroidism
- Neuromuscular or chest wall disorder
- Amyotrophic lateral sclerosis
- Spinal cord injury
- Diaphragmatic paralysis
- Myasthenia gravis
- Lambert-Eaton syndrome
- Toxic or metabolic myopathies
- Postpolio syndrome
- Charcot-Marie-Tooth syndrome[1]
Diagnostic Criteria
| “ |
(Note: In the absence of objective measurement of CO2, persistent low levels of hemoglobin oxygen saturation unassociated with apneic/hypopneic events may indicate hypoventilation.)
Specify whether:
Specify current severity:
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