Veno-occlusive disease: Difference between revisions

	Veno-occlusive disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Veno-occlusive disease from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Abdominal X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Veno-occlusive disease On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Veno-occlusive disease All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Veno-occlusive disease
CDC on Veno-occlusive disease
Veno-occlusive disease in the news
Blogs on Veno-occlusive disease
Directions to Hospitals Treating Veno-occlusive disease
Risk calculators and risk factors for Veno-occlusive disease

VisualWikitext

Latest revision as of 16:46, 27 January 2015

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: VOD, sinuosoidal obstruction syndrome

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Drug induced

Dactinomycin

Differentiating Veno-occlusive disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

@@ Line 5: / Line 5: @@
 '''''Synonyms and Keywords:''''' VOD, sinuosoidal obstruction syndrome
-==Overview==
+==[[Veno-occlusive disease overview|Overview]]==
-Veno-occlusive disease (VOD) is a disease of the liver in which the veins in the liver are obstructed or blocked.  VOD is a complication that occurs in up to 25% of [[bone marrow transplant]]ations, and may also occur after ingestion of certain plant [[alkaloids]].
-==Pathophysiology==
+==[[Veno-occlusive disease historical perspective|Historical Perspective]]==
-VOD is also known as '''sinuosoidal obstruction syndrome''' due to obstruction of the venous system.  Following bone marrow transplantation, VOD has been hypothesized to be due to injury to the hepatic venous [[endothelium]] from the conditioning regimen.
-==Prognosis==
-When associated with bone marrow transplant, VOD is fatal in over 30% of cases. Cases due to plant alkaloids often have a longer and more unpredictable course.
-==Diagnosis==
+==[[Veno-occlusive disease classification|Classification]]==
-===Symptoms===
-*[[Weight gain]]
+==[[Veno-occlusive disease pathophysiology|Pathophysiology]]==
-*[[Right upper quadrant pain]] due to [[hepatomegaly]]
-*[[Abdominal swelling]] due to [[ascites]]
+==[[Veno-occlusive disease causes|Causes]]==
+===Drug induced===
+* [[Dactinomycin]]
+==[[Veno-occlusive disease differential diagnosis|Differentiating Veno-occlusive disease from other Diseases]]==
+==[[Veno-occlusive disease epidemiology and demographics|Epidemiology and Demographics]]==
+==[[Veno-occlusive disease risk factors|Risk Factors]]==
+==[[Veno-occlusive disease screening|Screening]]==
-===Physical Examination===
+==[[Veno-occlusive disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
-====Abdominal Examination====
-*Tender [[hepatomegaly]]
-*[[Ascites]]
-===Laboratory Studies===
+==Diagnosis==
-*Increased [[bilirubin]]
+[[Veno-occlusive disease history and symptoms|History and Symptoms]] | [[Veno-occlusive disease physical examination|Physical Examination]] | [[Veno-occlusive disease laboratory findings|Laboratory Findings]] | [[Veno-occlusive disease abdominal x ray|Abdominal X Ray]] | [[Veno-occlusive disease CT|CT]] | [[Veno-occlusive disease MRI|MRI]] | [[Veno-occlusive disease ultrasound|Ultrasound]] | [[Veno-occlusive disease other imaging findings|Other Imaging Findings]] | [[Veno-occlusive disease other diagnostic studies|Other Diagnostic Studies]]
-*[[Renal failure]] may be present
 ==Treatment==
-Treatment for VOD is primarily supportive. In the BMT setting, [[defibrotide]] is an investigational treatment that may be promising.  Defibrotide is a polydeoxyribonucleotide; its mechanism of benefit in VOD is unclear, but has been attributed to its antithromboitc properties.
+[[Veno-occlusive disease medical therapy|Medical Therapy]] | [[Veno-occlusive disease surgery|Surgery]] | [[Veno-occlusive disease primary prevention|Primary Prevention]] | [[Veno-occlusive disease secondary prevention|Secondary Prevention]] | [[Veno-occlusive disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Veno-occlusive disease future or investigational therapies|Future or Investigational Therapies]]
-==Sources==
-Kumar, V., Abbas, A. and N. Fausto. 2004. ''Robbins & Cotran Pathologic Basis of Disease.'' Philadelphia: W. B. Saunders Company.
-==References==
+==Case Studies==
-{{Reflist|2}}
-==External link==
+[[Veno-occlusive disease case study one|Case #1]]
-* [http://www.asheducationbook.org/cgi/content/full/2004/1/372 American Society of Hematology education book] discussion of VOD
 [[Category:Hepatology]]
 [[Category:Hematology]]

Veno-occlusive disease: Difference between revisions

Latest revision as of 16:46, 27 January 2015

Drug induced

Diagnosis

Treatment

Case Studies

Navigation menu