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| __NOTOC__
| | #Redirect [[Neutropenia classification]] |
| {{Agranulocytosis}}
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| {{CMG}}
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| ==Overview==
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| ==Classification==
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| The term "agranulocytosis" derives from the Greek: ''a'', meaning ''without''; ''granulocyte'', a particular kind of cell; ''osis'', meaning ''condition'' [esp. ''disorder'']. Consequently, agranulocytosis is sometimes described as "no [[granulocyte]]s", but a total absence is not required for diagnosis.
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| However, "-osis" is commonly used in blood disorders to imply cell proliferation (such as in "leukocytosis"), while "-penia" to imply reduced cell numbers (as in "leukopenia"); for these reasons granulopenia is a more etymologically consistent term and as such should be preferred compared to "agranulocytosis" (which can be misinterpreted as "agranulocyt-osis", meaning proliferation of agranulocytes (i.e. lymphocytes and monocytes). Despite this, "agranulocytosis" remains the most widely used term for the condition.
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| The terms ''agranulocytosis'', ''[[granulocytopenia]]'' and ''[[neutropenia]]'' are sometimes used interchangeably. Agranulocytosis implies a more severe deficiency than granulocytopenia. Neutropenia indicates a deficiency of [[neutrophil]]s (the most common granulocyte cell) only.
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| To be precise, neutropenia is the term normally used to describe [[absolute neutrophil count]]s (ANC) of less than 500 cells per microlitre, whereas agranulocytosis is reserved for cases with ANC of less than 100 cells per microlitre.
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| The following terms can be used to specify the type of granulocyte referenced:
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| * Inadequate numbers of [[neutrophil]]s: [[neutropenia]] (most common)
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| * Inadequate numbers of [[eosinophil]]s: [[eosinopenia]] (uncommon)
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| * Inadequate numbers of [[basophil]]s: [[basopenia]] (very rare)
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| ==References==
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| {{Reflist|2}}
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| [[Category:Disease]]
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| [[Category:Hematology]]
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