Potassium iodide: Difference between revisions

Jump to navigation Jump to search
WikiBot (talk | contribs)
m Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +)
Kiran Singh (talk | contribs)
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Chembox new
{{DrugProjectFormSinglePage
|authorTag={{KS}}
|genericName=potassium iodide
|aOrAn=an
|drugClass=expectorant
|indicationType=treatment
|indication=of chronic pulmonary diseases where tenacious mucus complicates the problem, including [[asthma|bronchial asthma]], [[bronchitis]] and [[pulmonary emphysema]].
|adverseReactions=stomach upset, [[diarrhea]], [[nausea]], [[vomiting]], stomach pain, [[rash|skin rash]], and salivary gland swelling or tenderness, [[gastrointestinal bleeding]], [[confusion]]
|blackBoxWarningTitle=Warning Title
|blackBoxWarningBody=<i><span style="color:#FF0000;">Condition Name:</span></i> (Content)
|fdaLIADAdult===Indications==
For use as an expectorant in the symptomatic treatment of chronic pulmonary diseases where tenacious mucus complicates the problem, including [[asthma|bronchial asthma]], [[bronchitis]] and [[pulmonary emphysema]].
 
==Dosage==
* Adults - 0.3 ml (300 mg) or 0.6 ml (600 mg) diluted in one glassful of water, fruit juice or milk 3 to 4 times daily. To minimize gastric irritation, take with food or milk.
 
* This medication should be used no longer than necessary to produce the desired effect.
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
|offLabelAdultNoGuideSupport===Indications and Dosage==
* '''Induction of involution of thyroid''': 60-250 mg orally 3 times a day for 10 days before surgery.
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
|offLabelPedNoGuideSupport===Indications and Dosage==
* Induction of involution of thyroid
|contraindications=* Contraindicated in patients with a known sensitivity to iodides.
|warnings=* Potassium iodide can cause fetal harm, [[abnormal thyroid function]], and [[goiter]] when administered to a pregnant woman. Because of the possible development of fetal goiter, if the drug is used during pregnancy or if the patient becomes pregnant during therapy, apprise the patient of the potential hazard.
|clinicalTrials=* The most frequent adverse reactions to potassium iodide are stomach upset, [[diarrhea]], [[nausea]], [[vomiting]], [[stomach pain]], skin [[rash]], and salivary gland swelling or tenderness. Less frequent adverse reactions include [[gastrointestinal bleeding]], [[confusion]], [[arrythmia|irregular heartbeat]], [[numbness]], [[tingling]], pain or weakness in hands or feet, unusual [[tiredness]], weakness or heaviness of legs, fever, and swelling of neck or throat. [[Thyroid adenoma]], [[goiter]], and [[myxedema]] are possible side effects.
 
* Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. The symptoms of iodism include burning of mouth or throat, severe [[headache]], metallic taste, soreness of teeth and gums, symptoms of head cold, irritation of the eyes with swelling of the eyelids, unusual increase in salivation, acneform skin lesions in the seborrheic areas, and rarely, severe skin eruptions. If symptoms of iodism appear, the drug should be withdrawn and the patient given appropriate supportive therapy.
 
* Hypersensitivity to iodides may occur and may be manifested by [[angioedema]], cutaneous and mucosal hemorrhage, and signs and symptoms resembling [[serum sickness]], such as fever, [[arthralgia]], lymph node enlargement, and [[eosinophilia]].
|drugInteractions=* Concurrent use with lithium or [[antithyroid drugs]] may potentiate the [[hypothyroid]] and goitrogenic effects of these medications. Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in [[hyperkalemia]] and [[cardiac arrhythmias]] or [[cardiac arrest]].
|useInPregnancyFDA=Category D
|useInNursing=Potassium iodide is excreted in breast milk. Use by nursing mothers may cause skin [[rash]] and thyroid suppression in the infant.
|useInPed=* Safety and effectiveness in children have not been established.
|othersTitle=Others
|administration=Oral
|overdose=* Acute toxicity from potassium iodide is relatively rare. An occasional individual may show marked sensitivity and the onset of acute poisoning can occur immediately or hours after administration. [[Angioedema]], laryngeal edema and cutaneous hemorrhages may occur.
 
* Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. Symptoms of iodism typically disappear soon after discontinuation of the drug. Abundant fluid and salt intake aids in iodide elimination.
|drugBox={{chembox2
| verifiedrevid = 476997311
|  Name = Potassium iodide
|  Name = Potassium iodide
|  ImageFile = Potassium iodide.jpg
|  ImageFile = Potassium iodide.jpg
|  ImageFile1 = Potassium-iodide-3D-ionic.png
|  ImageFile1 = Potassium-iodide-3D-ionic.png
|  IUPACName = Potassium iodide
|  IUPACName = Potassium iodide
|  OtherNames = Kalium iodide,<br />knollide, potide
|  OtherNames =  
| Section1 = {{Chembox Identifiers
| Section1 = {{Chembox Identifiers
|  CASNo = 7681-11-0
ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4709
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 1C4QK22F9J
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D01016
| InChI = 1/HI.K/h1H;/q;+1/p-1
| InChIKey = NLKNQRATVPKPDG-REWHXWOFAG
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB06715
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 8346
| SMILES = [K+].[I-]
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1141
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/HI.K/h1H;/q;+1/p-1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = NLKNQRATVPKPDG-UHFFFAOYSA-M
| CASNo = 7681-11-0
|    CASNo_Ref = {{cascite|correct|CAS}}
|  PubChem = 4875
|  RTECS = TT2975000
|  RTECS = TT2975000
| ATCCode_prefix = R05
| ATCCode_suffix = CA02
| ATC_Supplemental = {{ATC|S01|XA04}}, {{ATC|V03|AB21}}
   }}
   }}
| Section2 = {{Chembox Properties
| Section2 = {{Chembox Properties
|  Formula = KI
|  Formula = KI
|  MolarMass = 166.00 g/mol
|  MolarMass = 166.0028 g/mol
|  Appearance = white crystalline solid
|  Appearance = white crystalline solid
|  Density = 3.13 g/cm<sup>3</sup>, solid
|  Density = 3.123 g/cm<sup>3</sup>
|  Solubility = 128 g/100 ml (6 °C)
|  Solubility = 128 g/100 ml (0 °C) <br> 140 g/100 mL (20 °C) <br> 176 g/100 mL (60°C) <br> 206 g/100 mL (100°C)
MeltingPt = 681 °C (954 K)
SolubleOther = 2 g/100 mL (ethanol) <br> soluble in [[acetone]] (1.31 g/100 mL) <br> slightly soluble in [[ether]], [[ammonia]]
BoilingPt = 1330 °C (1603 K)
MeltingPtC = 681
|  BoilingPtC = 1330
|  pKa =  
|  pKa =  
|  RefractIndex = 1.677
|  Viscosity = 1.0227 cP (733 °C)
   }}
   }}
| Section3 = {{Chembox Structure
| Section3 = {{Chembox Structure
|  Coordination =  
|  Coordination =  
|  CrystalStruct =  
|  CrystalStruct = cubic
|  Dipole =
|  Dipole =
  }}
| Section4 = {{Chembox Thermochemistry
|  DeltaHf = -327.6 kJ/mol
|  HeatCapacity = 52.73 J/mol K
   }}
   }}
| Section7 = {{Chembox Hazards
| Section7 = {{Chembox Hazards
|  ExternalMSDS = [http://www.jtbaker.com/msds/englishhtml/p5906.htm External MSDS]
|  ExternalMSDS = [http://hazard.com/msds/mf/baker/baker/files/p5906.htm External MSDS]
MainHazards = Slightly hazardous
EUIndex = Not listed
|  NFPA-H = 1
|  NFPA-H = 1
|  NFPA-F =
|  NFPA-F = 0
|  NFPA-R =
|  NFPA-R = 0
|  RPhrases = {{R36}}, {{R38}}, {{R42}}-{{R43}}, {{R61}}
|  RPhrases =  
|  SPhrases = {{S26}}, {{S36}}-{{S37}}, {{S39}}, {{S45}}
|  SPhrases =  
   }}
   }}
| Section8 = {{Chembox Related
| Section8 = {{Chembox Related
|  OtherAnions = [[potassium bromide]]<br />[[potassium chloride]]
|  OtherAnions = [[Potassium fluoride]]<br/>[[Potassium chloride]]<br/>[[Potassium bromide]]
|  OtherCations = [[lithium iodide]]<br />[[sodium iodide]]<br />[[rubidium iodide]]<br />[[caesium iodide]]
|  OtherCations = [[Lithium iodide]]<br/>[[Sodium iodide]]<br/>[[Rubidium iodide]]<br/>[[Caesium iodide]]
   }}
   }}
}}
}}
{{CMG}}
|mechAction=* Potassium iodide is thought to act as an expectorant by increasing respiratory tract secretions and thereby decreasing the viscosity of mucus.
|howSupplied=* SSKI® (Potassium Iodide Oral Solution, USP) is supplied in 1 fluid ounce (30 ml) bottles (NDC 0245-0003-31) with a calibrated dropper marked to deliver 0.3 ml (300 mg) and 0.6 ml (600 mg); and 8 fluid ounce (237 ml) bottles (NDC 0245-0003-08). Inactive ingredient: Sodium thiosulfate as a preservative.


{{EH}}
'''Dispense in tight, light-resistant containers with child-resistant closures.'''


'''Potassium iodide''' is a white [[crystal]]line [[salt]] with [[chemical formula]], used in photography and radiation treatment. It finds widespread application as an iodide source because it is less [[hygroscopic]] than [[sodium iodide]], making it easier to work with. KI can turn yellow upon heating in air or upon standing in moist air for long periods, because of [[oxidation]] of the [[iodide]] to [[iodine]].
Notice: When exposed to cold temperatures, crystallization may occur, but on warming and shaking, the crystals will redissolve. If the solution turns brownish-yellow in color, it should be discarded.
|storage=* Store at controlled room temperature, 15-30°C (59-86°F). Keep tightly closed and protected from light.
|alcohol=Alcohol-Potassium iodide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
|brandNames=SSKI
|nlmPatientInfo=(Link to patient information page)
|drugShortage=Drug Shortage
}}
{{LabelImage
|fileName=Potassium iodide ingredients and appearance.png
}}
{{LabelImage
|fileName=Potassium iodide fig01.jpg
}}


== Chemical properties ==
[[Category:Expectorants]]
'''Potassium iodide''' behaves as a simple [[ion]]ic [[salt]], K<sup>+</sup>I<sup>−</sup>.  Since the [[iodide]] ion is a mild [[Redox|reducing agent]], I<sup>−</sup> is easily oxidised to [[iodine|I<sub>2</sub>]] by powerful [[redox|oxidising agents]] such as [[chlorine]]:
 
:2 KI([[aqueous|aq]])  +  [[Chlorine|Cl<sub>2</sub>]](aq)  →  2 [[Potassium chloride|KCl]]  +  [[Iodine|I<sub>2</sub>]](aq)
 
Even air will oxidize iodide as evidenced by the observation of a purple extract when KI is rinsed with [[dichloromethane]].  Under acidic conditions, KI is oxidised even more easily, due to the formation of [[hydroiodic acid]] (HI), which is a powerful reducing agent.<ref>N. N. Greenwood, A. Earnshaw, ''Chemistry of the Elements'', Pergamon Press, Oxford, UK, 1984</ref><ref>''Handbook of Chemistry and Physics'', 71st edition, CRC Press, Ann Arbor, Michigan, 1990</ref><ref>''The Merck Index'', 7th edition, Merck & Co., Rahway, New Jersey, 1960</ref><ref>H. Nechamkin, ''The Chemistry of the Elements'', McGraw-Hill, New York, 1968</ref>
 
KI forms [[triiodide|I<sub>3</sub><sup>−</sup>]] when combined with elemental [[iodine]].
:KI(aq)  +  [[Iodine|I<sub>2</sub>]]([[solid|s]])  →  KI<sub>3</sub>(aq)
Unlike I<sub>2</sub>, I<sub>3</sub><sup>−</sup> salts can be highly water-soluble.  <!--the following statement is untrue or at least imprecise and confusing, because I2 no longer exists in the presence of I−: "this reaction is frequently used to render I<sub>2</sub> more soluble in water"-->  I<sub>2</sub> and  I<sub>3</sub><sup>−</sup> have virtually identical redox potentials (0.535 and 0.536 V vs NHE, respectively), i.e. they are both mild oxidants relative to H<sub>2</sub>.  Therefore, this reaction allows the [[iodine]] to be used in aqueous solutions for [[redox]] [[titration]]s.
 
Potassium iodide also serves in some organic reactions as a source of iodide ion (see "uses" below).
 
== Physical Properties ==
 
It occurs as odourless, colourless, transparent or somewhat opaque crystals or white granular powder. It is slightly hygroscopic, the taste is saline and slightly bitter.
On long exposure to air, it becomes yellow due to the liberation of iodine and small quantities of iodate may be formed.
 
== Uses ==
Potassium iodide is used in photography, in the preparation of [[silver(I) iodide]] for  high speed [[photographic film]]:
 
:KI([[aqueous|aq]])  +  [[Silver nitrate|AgNO<sub>3</sub>]]([[aqueous|aq]])  →  [[Silver iodide|AgI]]([[solid|s]])  +  [[Potassium nitrate|KNO<sub>3</sub>]]([[aqueous|aq]])
 
Potassium iodide is also added to [[sodium chloride|table salt]] in small quantities to make it "iodized". In a saturated solution, it is also used as an [[expectorant]] to treat lung congestion.
 
KI is often used as a source of [[iodide]] ion in [[organic synthesis]].  A useful application is in the preparation of aryl iodides from arenediazonium salts.<ref>L. G. Wade, ''Organic Chemistry'', 5th ed., pp. 871-2, Prentice Hall, Upper Saddle RIver, New Jersey, 2003</ref><ref>J. March, ''Advanced Organic Chemistry'', 4th ed., pp. 670-1, Wiley, New York, 1992</ref> For example:
 
[[Image:KI Sandmeyer.png|400px]]
 
Saturated solution of potassium iodide is also used as treatment for  [[sporotrichosis]], a fungal infection.
 
In medical use, it can also serve as an antiseptic for people suffering from sore throat. The dose is 0.5 g-1.0 g in 100 mL, with the accompany of iodine (0.5 g-1.0 g in 100 mL).
 
KI is also used as a [[fluorescence quenching]] agent in biomedical research because of collisional quenching by its iodide ion.
 
In aqueous solution with elemental iodine, it acts as a gold etchant and will attack and dissolve gold surfaces.
 
==Radiation protection==
Potassium iodide was also FDA approved in 1982 to protect the [[thyroid]] from [[radioiodine|radioactive iodine]]. In the event of an accident or attack at a nuclear power plant, or fallout from a nuclear bomb, several volatile fission product radionuclides may be released. [[Iodine-131|<sup>131</sup>I]] is a common fission by-product and is particularly dangerous as the body concentrates it only in the thyroid gland which may lead to thyroid cancer. By saturating the body with a source of stable iodine prior to exposure, any radioactive <sup>131</sup>I inhaled or ingested becomes the excess in the blood system and is excreted through the kidneys. Potassium iodide cannot protect against any other causes of [[radiation poisoning]], however, nor can it provide any degree of protection against a dirty bomb unless the bomb happens to contain a significant amount of [[iodine-131|radioactive iodine]]. In case of a [[Nuclear fallout|nuclear emergency]], ''[[iodine]]'' used for the cleaning of wounds should '''not''' be ingested, as it is [[poisonous]]. Only 3 brands of potassium iodide have been tested and approved for use by the [[FDA]]  as a thyroid blocking agent during exposure to radioactive iodine (Iosat, ThyroShield and Thyro-safe) and hence [[potassium iodate]] is not approved in the U.S. for this purpose.
 
{| class="wikitable"
|+ Recommended Dosage for Radiological Emergencies involving radioactive iodine<ref>''Guidelines for Iodine Prophylaxis following Nuclear Accidents'', [[World Health Organization]], Update 1999</ref>
! Age
! KI in mg
!
|-
| Over 12 years old
| 130
|
|-
| 3 - 12 years old
| 65
|
|-
| 1 - 36 months old
| 32
|
|-
| < 1 month old
| 16
|
|}
 
See [[fission products]] and the external links for more details.
 
== Precautions ==
Mild irritant, wear gloves. Chronic overexposure can have adverse effects on the thyroid.
 
== References ==
{{reflist|2}}
 
==External links==
* {{ATC|R05|CA02}}
* [http://www.who.int/ionizing_radiation/pub_meet/en/Iodine_Prophylaxis_guide.pdf World Health Organization's guidelines for iodine prophylaxis following a nuclear accident]
 
{{Antidotes}}
 
[[Category:Potassium compounds]]
[[Category:Metal halides]]
[[Category:Iodides]]
[[Category:Iodides]]
[[Category:Disaster preparedness]]
[[Category:Drug]]
[[Category:Radiobiology]]
[[Category:Photographic chemicals]]
[[Category:Food additives]]
[[Category:Expectorants]]
 
[[bg:Калиев йодид]]
[[de:Kaliumiodid]]
[[es:Yoduro de potasio]]
[[it:Ioduro di potassio]]
[[lv:Kālija jodīds]]
[[hu:Kálium-jodid]]
[[nl:Kaliumjodide]]
[[ja:ヨウ化カリウム]]
[[nn:Kaliumjodid]]
[[pl:Jodek potasu]]
[[pt:Iodeto de potássio]]
[[ru:Иодид калия]]
[[sr:Калијум јодид]]
[[sv:Kaliumjodid]]
[[zh:碘化钾]]
 
{{WH}}
{{WS}}

Latest revision as of 18:31, 9 March 2015

Potassium iodide
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Potassium iodide is an expectorant that is FDA approved for the treatment of of chronic pulmonary diseases where tenacious mucus complicates the problem, including bronchial asthma, bronchitis and pulmonary emphysema.. Common adverse reactions include stomach upset, diarrhea, nausea, vomiting, stomach pain, skin rash, and salivary gland swelling or tenderness, gastrointestinal bleeding, confusion.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

For use as an expectorant in the symptomatic treatment of chronic pulmonary diseases where tenacious mucus complicates the problem, including bronchial asthma, bronchitis and pulmonary emphysema.

Dosage

  • Adults - 0.3 ml (300 mg) or 0.6 ml (600 mg) diluted in one glassful of water, fruit juice or milk 3 to 4 times daily. To minimize gastric irritation, take with food or milk.
  • This medication should be used no longer than necessary to produce the desired effect.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Potassium iodide in adult patients.

Non–Guideline-Supported Use

Indications and Dosage

  • Induction of involution of thyroid: 60-250 mg orally 3 times a day for 10 days before surgery.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Potassium iodide FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Potassium iodide in pediatric patients.

Non–Guideline-Supported Use

Indications and Dosage

  • Induction of involution of thyroid

Contraindications

  • Contraindicated in patients with a known sensitivity to iodides.

Warnings

  • Potassium iodide can cause fetal harm, abnormal thyroid function, and goiter when administered to a pregnant woman. Because of the possible development of fetal goiter, if the drug is used during pregnancy or if the patient becomes pregnant during therapy, apprise the patient of the potential hazard.

Adverse Reactions

Clinical Trials Experience

  • Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. The symptoms of iodism include burning of mouth or throat, severe headache, metallic taste, soreness of teeth and gums, symptoms of head cold, irritation of the eyes with swelling of the eyelids, unusual increase in salivation, acneform skin lesions in the seborrheic areas, and rarely, severe skin eruptions. If symptoms of iodism appear, the drug should be withdrawn and the patient given appropriate supportive therapy.

Postmarketing Experience

There is limited information regarding Potassium iodide Postmarketing Experience in the drug label.

Drug Interactions

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): Category D
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Potassium iodide in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Potassium iodide during labor and delivery.

Nursing Mothers

Potassium iodide is excreted in breast milk. Use by nursing mothers may cause skin rash and thyroid suppression in the infant.

Pediatric Use

  • Safety and effectiveness in children have not been established.

Geriatic Use

There is no FDA guidance on the use of Potassium iodide in geriatric settings.

Gender

There is no FDA guidance on the use of Potassium iodide with respect to specific gender populations.

Race

There is no FDA guidance on the use of Potassium iodide with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Potassium iodide in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Potassium iodide in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Potassium iodide in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Potassium iodide in patients who are immunocompromised.

Others

Administration and Monitoring

Administration

Oral

Monitoring

There is limited information regarding Potassium iodide Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Potassium iodide and IV administrations.

Overdosage

  • Acute toxicity from potassium iodide is relatively rare. An occasional individual may show marked sensitivity and the onset of acute poisoning can occur immediately or hours after administration. Angioedema, laryngeal edema and cutaneous hemorrhages may occur.
  • Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. Symptoms of iodism typically disappear soon after discontinuation of the drug. Abundant fluid and salt intake aids in iodide elimination.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox RefractIndexTemplate:Chembox ViscosityTemplate:Chembox StructureTemplate:Chembox ThermochemistryTemplate:Chembox NFPATemplate:Chembox OtherAnionsTemplate:Chembox OtherCationsTemplate:Chembox Supplement
Template:Chembox header2 | Potassium iodide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG
UNII
Properties
KI
Molar mass 166.0028 g/mol
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Mechanism of Action

  • Potassium iodide is thought to act as an expectorant by increasing respiratory tract secretions and thereby decreasing the viscosity of mucus.

Structure

There is limited information regarding Potassium iodide Structure in the drug label.

Pharmacodynamics

There is limited information regarding Potassium iodide Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Potassium iodide Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Potassium iodide Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Potassium iodide Clinical Studies in the drug label.

How Supplied

  • SSKI® (Potassium Iodide Oral Solution, USP) is supplied in 1 fluid ounce (30 ml) bottles (NDC 0245-0003-31) with a calibrated dropper marked to deliver 0.3 ml (300 mg) and 0.6 ml (600 mg); and 8 fluid ounce (237 ml) bottles (NDC 0245-0003-08). Inactive ingredient: Sodium thiosulfate as a preservative.

Dispense in tight, light-resistant containers with child-resistant closures.

Notice: When exposed to cold temperatures, crystallization may occur, but on warming and shaking, the crystals will redissolve. If the solution turns brownish-yellow in color, it should be discarded.

Storage

  • Store at controlled room temperature, 15-30°C (59-86°F). Keep tightly closed and protected from light.

Images

Drug Images

{{#ask: Page Name::Potassium iodide |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Potassium iodide |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Potassium iodide Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Potassium iodide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

SSKI

Look-Alike Drug Names

There is limited information regarding Potassium iodide Look-Alike Drug Names in the drug label.

Drug Shortage Status

Drug Shortage

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

{{#subobject:

 |Label Page=Potassium iodide
 |Label Name=Potassium iodide ingredients and appearance.png

}}

{{#subobject:

 |Label Page=Potassium iodide
 |Label Name=Potassium iodide fig01.jpg

}}