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==Overview==
==Overview==
This is a list of specific [[Wiktionary:pharmacological agent|pharmacologic agents]] that are known to be of use in the treatment of [[cancer]], otherwise known as '''[[Wiktionary:chemotherapeutic agent|chemotherapeutic agents]]'''. This list is organized by "type" of agent, though the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection.
This is a '''list of chemotherapeutic agents''' that are known to be of use in [[chemotherapy]] for [[cancer]]. A full alphabetical listing is included after the categorical listing.


A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into [[chemotherapy regimens]] for polychemotherapy (combination chemotherapy).


{{listdev}}
== Chemotherapeutic Agents by Category ==


== Alkylating agents ==
=== Alkylating agents ===
* [[Cyclophosphamide]]
* [[Mechlorethamine]]
* [[Chlorambucil]]
* [[Melphalan]]


== Anthracyclines ==
====== Nitrogen mustards ======
''article on [[anthracycline]]s''
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Daunorubicin]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Doxorubicin]]
* [[Estramustine |Estramustine  (Emcyt)]]
* [[Epirubicin]]
* [[Ifosfamide|Ifosfamide (Iflex)]]
* [[Idarubicin]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Mitoxantrone]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Valrubicin]]


== Cytoskeletal disruptors ==
====== Ethylenimines ======
* [[Paclitaxel]]
* [[Thiotepa|Thiotepa (Tepadina)]]
* [[Docetaxel]]


== Epothilones ==
====== Methylhydrazines ======
''article on [[epothilone]]s''
* [[Procarbazine|Procarbazine (Matulane)]]


== Inhibitors of topoisomerase II ==
====== Alkylsulfonates ======
* [[Etoposide]]
* [[Busulfan|Busulfan (Myleran)]]
* [[Teniposide]]
* [[Tafluposide]]


== Nucleotide analogs and precursor analogs ==
====== Nitrosoureas ======
* [[Azacitidine]]
* [[Bendamustine|Bendamustine (Treanda)]]  
* [[Azathioprine]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Capecitabine]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Cytarabine]]
* [[Streptozocin|Streptozocin (Zanosar)]]
* [[Doxifluridine]]
* [[Fluorouracil]]
* [[Gemcitabine]]
* [[Mercaptopurine]]
* [[Methotrexate]]
* [[Tioguanine]] (formerly Thioguanine)


== Peptide antibiotics ==
====== Triazenes ======
* [[Bleomycin]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
* [[Temozolomide|Temozolomide (Temodar)]]


== Platinum-based agents ==
====== Platinum coordination complexes ======
* [[Carboplatin]]
* [[Carboplatin|Carboplatin (Paraplatin)]]
* [[Cisplatin]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Oxaliplatin]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]


== Retinoids ==
----
* [[All-trans retinoic acid]]


== Vinca alkaloids and derivatives ==
=== Antimetabolites ===
* [[Vinblastine]]
* [[Vincristine]]
* [[Vindesine]]
* [[Vinorelbine]]


== Full alphabetical listing ==
====== Folic acid analogs ======
* [[All-trans retinoic acid]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Azacitidine]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Azathioprine]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Bleomycin]]
* [[Carboplatin]]
* [[Capecitabine]]
* [[Cisplatin]]
* [[Chlorambucil]]
* [[Cyclophosphamide]]
* [[Cytarabine]]
* [[Daunorubicin]]
* [[Docetaxel]]
* [[Doxifluridine]]
* [[Doxorubicin]]
* [[Epirubicin]]
* [[Epothilone]]
* [[Etoposide]]
* [[Fluorouracil]]
* [[Gemcitabine]]
* [[Hydroxyurea]] ''requires categorization''
* [[Idarubicin]]
* [[Imatinib]]
* [[Mechlorethamine]]
* [[Mercaptopurine]]
* [[Methotrexate]]
* [[Mitoxantrone]]
* [[Oxaliplatin]]
* [[Paclitaxel]]
* [[Pemetrexed]]
* [[Teniposide]]
* [[Tioguanine]]
* [[Valrubicin]]
* [[Vinblastine]]
* [[Vincristine]]
* [[Vindesine]]
* [[Vinorelbine]]


====== Pyrimidine analogs ======
* [[Azacytidine|Azacytidine (Vidaza)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]
====== Purine analogs ======
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Fludarabine|Fludarabine (Fludara)]]
* [[Mercaptopurine|Mercaptopurine (Purinethol)]]
* [[Nelarabine|Nelarabine (Arranon)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
====== Ribonucleotide reductase inhibitors ======
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
----
=== Natural products ===
====== Vinca alkaloids ======
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
====== Taxanes ======
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]
====== Epipodophyllotoxins ======
* [[Etoposide|Etoposide (Vespid)]]
* [[Teniposide|Teniposide (Vumon)]]
====== Camptothecins ======
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Topotecan|Topotecan (Hycamtin)]]
====== Antineoplastic antibiotics ======
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Daunorubicin |Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Idarubicin|Idarubicin (Idamycin)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Valrubicin|Valrubicin (Valstar)]]
====== Antineoplastic enzymes ======
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
----
=== Hormones and Antagonists ===
====== Adrenocortical suppressants ======
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Mitotane|Mitotane (Lysodren)]]
* [[Trilostane|Trilostane (Modrenal)]]
====== Glucocorticoids ======
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Prednisone|Prednisone (Deltasone)]]
====== Progestins ======
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
====== Estrogens ======
* [[Esterified estrogens|Esterified estrogens (Menest)]]
====== Anti-estrogens ======
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Toremifene|Toremifene (Fareston)]]
====== Aromatase inhibitors ======
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Letrozole|Letrozole (Femara)]]
====== Androgens ======
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Testolactone|Testolactone (Teslac)]]
====== Anti-androgens ======
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone (Zytiga)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
====== LHRH agonists ======
* [[Triptorelin|Triptorelin (Trelstar)]]
===== GnRH agonists =====
* [[Buserelin|Buserelin (Superfact)]]
* [[Goserelin|Goserelin (Zoladex)]]
* [[Leuprolide|Leuprolide (Lupron)]]
===== GnRH antagonists =====
* [[Degarelix|Degarelix (Firmagon)]]
----
=== Biologics ===
===== Monoclonal antibodies =====
====== Anti-CD3 antibodies ======
* [[Catumaxomab|Catumaxomab (Removab)]]
====== Anti-CD3 & anti-CD19 antibodies ======
* [[Blinatumomab|Blinatumomab (Blincyto)]]
====== Anti-CD20 antibodies ======
* [[Rituximab|Rituximab (Rituxan)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin))]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
* [[Tositumomab|Tositumomab (Bexxar)]]
====== Anti-CD30 antibodies ======
* [[Brentuximab|Brentuximab (Adcetris)]]
====== Anti-CD33 antibodies ======
* [[Gemtuzumab|Gemtuzumab (Mylotarg)]]
====== Anti-CD52 antibodies ======
* [[Alemtuzumab|Alemtuzumab (Campath)]]
====== Anti-CTLA–4 antibodies ======
* [[Ipilimumab|Ipilimumab (Yervoy)]]
====== Anti-EGFR (ErbB1) antibodies ======
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
====== Anti-PD–1 antibodies ======
* [[Nivolumab |Nivolumab (Opdivo)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
====== Anti-HER2/neu (ErbB2) antibodies ======
* [[Ado-trastuzumab emtansine|Ado-trastuzumab (Kadcyla)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
====== Anti-VEGF antibodies ======
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
===== IL-6 inhibitors =====
* [[Siltuximab|Siltuximab (Sylvant)]]
* [[Tocilizumab|Tocilizumab (Actemra)]]
===== Immunotherapy =====
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
----
=== Hematopoietic Growth Factors ===
===== Erythrocyte growth factors =====
* [[Erythropoietin|Erythropoietin (Procrit)]]
===== Granulocyte growth factors =====
* [[Filgrastim|Filgrastim (Neupogen)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Sargramostim|Sargramostin (Leukine, Leukomax)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
===== Megakaryocyte growth factors =====
* [[Eltrombopag|Eltrombopag (Promacta)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]
----
=== Supportive Medications ===
===== Chemotherapy protective agents =====
* [[Amifostine|Amifostine (Ethyol)]]
* [[Cyanocobalamin|Cyanocobalamin (Cobal)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Rasburicase|Rasburicase (Elitek)]]
===== Antiemetic agents =====
* [[Netupitant and palonosetron |Netupitant and palonosetron (Akynzeo)]]
===== RANK ligand inhibitors =====
* [[Denosumab|Denosumab (Xgeva)]]
===== Calcium regulators =====
* [[Gallium nitrate|Gallium nitrate (Ganite)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Zoledronic Acid|Zoledronic Acid (Zometa)]]
----
=== Miscellaneous ===
===== Mitotic inhibitors =====
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Cabazitaxel|Cabazitaxel (Jevtana)]]
* [[Eribulin|Eribulin (Halaven)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
===== HDAC inhibitors =====
* [[Belinostat|Belinostat (Beleodaq)]]
* [[Romidepsin|Romidepsin (Istodax)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
===== Hedgehog pathway inhibitors =====
* [[Vismodegib|Vismodegib (Erivedge)]]
===== Immunomodulatory drugs (IMiDs) =====
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
===== Kinase inhibitors =====
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Axitinib|Axitinib (Inlyta)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenvatinib|Lenvatinib (Lenvima)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
===== Photosensitizing agents =====
* [[Aminolevulinic acid |Aminolevulinic acid (Levulan)]]
* [[Porfimer|Porfimer (Photofrin)]]
===== Proteasome inhibitors =====
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
===== Radioactive agents =====
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
===== Somatostatin analogs =====
* [[Octreotide|Octreotide (Octreotide)]]
===== Differentiating agents =====
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
===== Orphan drugs =====
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Trabectedin|Trabectedin (Yondelis)]]
== Chemotherapeutic Agents in Alphabetical Order ==
{{Columns-list|3|
* [[Abarelix|Abarelix (Plenaxis)]]
* [[Abiraterone|Abiraterone acetate (Zytiga)]]
* [[Ado-trastuzumab emtansine|Ado-trastuzumab emtansine (Kadcyla)]]
* [[Afatinib|Afatinib (Gliotrif)]]
* [[Aldesleukin|Aldesleukin (Proleukin)]]
* [[Alemtuzumab|Alemtuzumab (Campath)]]
* [[Altretamine|Altretamine (Hexalen)]]
* [[Amifostine|Amifostine (Ethyol)]]
* [[Aminoglutethimide|Aminoglutethimide (Cytadren)]]
* [[Aminolevulinic acid|Aminolevulinic acid (Levulan)]]
* [[Amsacrine|Amsacrine (Amsidine)]]
* [[Anastrozole|Anastrozole (Arimidex)]]
* [[Arsenic trioxide|Arsenic trioxide (Trisenox)]]
* [[Asparaginase Erwinia chrysanthemi|Asparaginase Erwinia chrysanthemi (Erwinaze)]]
* [[Axitinib|Axitinib (Inlyta)]]
* [[Azacytidine|Azacytidine (Vidaza)]]
* [[Belinostat|Belinostat (Beleodaq)]]
* [[Bendamustine|Bendamustine (Treanda)]]
* [[Bevacizumab|Bevacizumab (Avastin)]]
* [[Bexarotene|Bexarotene (Targretin)]]
* [[Bicalutamide|Bicalutamide (Casodex)]]
* [[Bleomycin|Bleomycin (Blenoxane)]]
* [[Blinatumomab|Blinatumomab (Blincyto)]]
* [[Bortezomib|Bortezomib (Velcade)]]
* [[Bosutinib|Bosutinib (Bosulif)]]
* [[Brentuximab vedotin|Brentuximab vedotin (Adcetris)]]
* [[Buserelin|Buserelin (Suprefact)]]
* [[Busulfan|Busulfan (Myleran-oral)]]
* [[Cabazitaxel|Cabazitaxel (Jevtana)]]
* [[Cabozantinib|Cabozantinib (Cometriq)]]
* [[Capecitabine|Capecitabine (Xeloda)]]
* [[Carboplatin|Carboplatin (Paraplatin)]]
* [[Carfilzomib|Carfilzomib (Kyprolis)]]
* [[Carmustine|Carmustine (BiCNU)]]
* [[Catumaxomab|Catumaxomab (Removab)]]
* [[Ceritinib|Ceritinib (Zykadia)]]
* [[Cetuximab|Cetuximab (Erbitux)]]
* [[Chlorambucil|Chlorambucil (Leukeran)]]
* [[Cisplatin|Cisplatin (Platinol)]]
* [[Cladribine|Cladribine (Leustatin)]]
* [[Clofarabine|Clofarabine (Clolar)]]
* [[Crizotinib|Crizotinib (Xalkori)]]
* [[Cyclophosphamide|Cyclophosphamide (Cytoxan)]]
* [[Cytarabine|Cytarabine (Cytosar)]]
* [[Cytarabine liposome|Cytarabine liposome (DepoCyt)]]
* [[Dabrafenib|Dabrafenib (Tafinlar)]]
* [[Dacarbazine|Dacarbazine (Dtic-Dome)]]
* [[Dactinomycin|Dactinomycin (Cosmegen)]]
* [[Dasatinib|Dasatinib (Sprycel)]]
* [[Daunorubicin|Daunorubicin (Cerubidine)]]
* [[Daunorubicin liposome|Daunorubicin liposome (Daunoxome)]]
* [[Decitabine|Decitabine (Dacogen)]]
* [[Degarelix|Degarelix (Firmagon)]]
* [[Denileukin diftitox|Denileukin diftitox (Ontak)]]
* [[Denosumab|Denosumab (Xgeva)]]
* [[Dexamethasone|Dexamethasone (Decadron)]]
* [[Dexrazoxane|Dexrazoxane (Zinecard)]]
* [[Docetaxel|Docetaxel (Taxotere)]]
* [[Doxorubicin|Doxorubicin (Adriamycin, Rubex)]]
* [[Doxorubicin liposome|Doxorubicin liposome (Doxil, Lipodox)]]
* [[Enzalutamide|Enzalutamide (Xtandi)]]
* [[Epirubicin|Epirubicin (Ellence)]]
* [[Eribulin mesylate|Eribulin (Halaven)]]
* [[Erlotinib|Erlotinib (Tarceva)]]
* [[Erythropoietin|Erythropoietin (Epogen, Procrit)]]
* [[Esterified estrogens|Esterified estrogens (Menest)]]
* [[Estramustine|Estramustine (Emcyt)]]
* [[Etoposide|Etoposide (Vespid)]]
* [[Everolimus|Everolimus (Afinitor)]]
* [[Exemestane|Exemestane (Aromasin)]]
* [[Filgrastim|Filgrastim (Neupogen)]]
* [[Floxuridine|Floxuridine (FUDR)]]
* [[Fludarabine|Fludarabine (Fludara)]]
* [[Fluorouracil|Fluorouracil (Adrucil, Efudex)]]
* [[Fluoxymesterone|Fluoxymesterone (Halotestin)]]
* [[Flutamide|Flutamide (Eulexin)]]
* [[Folinic acid|Folinic acid (Leucovorin Calcium)]]
* [[Formestane|Formestane (Lentaron)]]
* [[Fulvestrant|Fulvestrant (Faslodex)]]
* [[Gallium nitrate|Gallium Nitrate (Ganite)]]
* [[Gefitinib|Gefitinib (Iressa)]]
* [[Gemcitabine|Gemcitabine (Gemzar)]]
* [[Gemtuzumab ozogamicin|Gemtuzumab ozogamicin (Mylotarg)]]
* [[Glucarpidase|Glucarpidase (Voraxaze)]]
* [[Goserelin acetate|Goserelin Acetate (Zoladex)]]
* [[Hydroxyurea|Hydroxyurea (Hydrea)]]
* [[Ibritumomab tiuxetan|Ibritumomab tiuxetan (Zevalin)]]
* [[Ibrutinib|Ibrutinib (Imbruvica)]]
* [[Idarubicin|Idarubicin (Idamycin)]]
* [[Idelalisib|Idelalisib (Zydelig)]]
* [[Ifosfamide|Ifosfamide (Ifex)]]
* [[Imatinib|Imatinib (Gleevec)]]
* [[Interferon alfa-2b|Interferon alfa-2b (Intron A)]]
* [[Ipilimumab|Ipilimumab (Yervoy)]]
* [[Irinotecan|Irinotecan (Camptosar)]]
* [[Ixabepilone|Ixabepilone (Ixempra)]]
* [[L-Asparaginase|L-Asparaginase (Elspar)]]
* [[Lapatinib|Lapatinib (Tykerb)]]
* [[Lenalidomide|Lenalidomide (Revlimid)]]
* [[Lenvatinib|Lenvatinib (Lenvima)]]
* [[Letrozole|Letrozole (Femara)]]
* [[Leuprolide|Leuprolide (Lupron)]]
* [[Levoleucovorin|Levoleucovorin (Fusilev)]]
* [[Lomustine|Lomustine (CeeNU)]]
* [[Mechlorethamine|Mechlorethamine (Mustargen)]]
* [[Medroxyprogesterone acetate|Medroxyprogesterone acetate (Provera)]]
* [[Megestrol|Megestrol (Megace)]]
* [[Melphalan|Melphalan (Alkeran)]]
* [[Mercaptopurine|Mercaptopurine (Purinethol)]]
* [[Mesna|Mesna (Mesnex)]]
* [[Methotrexate|Methotrexate (Mexate, Folex)]]
* [[Mitomycin C|Mitomycin C (Mutamycin)]]
* [[Mitotane|Mitotane (Lysodren)]]
* [[Mitoxantrone|Mitoxantrone (Novantrone)]]
* [[Nelarabine|Nelarabine (Arranon)]]
* [[Netupitant and palonosetron|Netupitant and palonosetron (Akynzeo)]]
* [[Nilotinib|Nilotinib (Tasigna)]]
* [[Nilutamide|Nilutamide (Nilandron)]]
* [[Nivolumab|Nivolumab (Opdivo)]]
* [[Obinutuzumab|Obinutuzumab (Gazyva)]]
* [[Octreotide|Octreotide (Octreotide)]]
* [[Ofatumumab|Ofatumumab (Arzerra)]]
* [[Olaparib|Olaparib (Lynparza)]]
* [[Omacetaxine|Omacetaxine (Synribo)]]
* [[Oprelvekin|Oprelvekin (Neumega)]]
* [[Oxaliplatin|Oxaliplatin (Eloxatin)]]
* [[Paclitaxel|Paclitaxel (Taxol, Onxol)]]
* [[Paclitaxel protein-bound|Paclitaxel protein-bound (Abraxane)]]
* [[Palbociclib|Palbociclib (Ibrance)]]
* [[Pamidronate|Pamidronate (Aredia)]]
* [[Panitumumab|Panitumumab (Vectibix)]]
* [[Pazopanib|Pazopanib (Votrient)]]
* [[Pegaspargase|Pegaspargase (Oncaspar)]]
* [[Pegfilgrastim|Pegfilgrastim (Neulasta)]]
* [[Peginterferon alfa-2a|Peginterferon alfa-2a (Pegasys)]]
* [[Pegylated interferon alfa-2b|Peginterferon alfa-2b (Sylatron)]]
* [[Pembrolizumab|Pembrolizumab (Keytruda)]]
* [[Pemetrexed|Pemetrexed (Alimta)]]
* [[Pentostatin|Pentostatin (Nipent)]]
* [[Pertuzumab|Pertuzumab (Perjeta)]]
* [[Pixantrone|Pixantrone (Pixuvri)]]
* [[Plerixafor|Plerixafor (Mozobil)]]
* [[Plicamycin|Plicamycin (Mithracin)]]
* [[Pomalidomide|Pomalidomide (Pomalyst)]]
* [[Ponatinib|Ponatinib (Iclusig)]]
* [[Porfimer|Porfimer (Photofrin)]]
* [[Pralatrexate|Pralatrexate (Folotyn)]]
* [[Prednisone|Prednisone (Deltasone)]]
* [[Procarbazine|Procarbazine (Matulane)]]
* [[Radium-223 chloride|Radium-223 chloride (Xofigo)]]
* [[Raloxifene|Raloxifene (Evista)]]
* [[Raltitrexed|Raltitrexed (Tomudex)]]
* [[Ramucirumab|Ramucirumab (Cyramza)]]
* [[Ranpirnase|Ranpirnase (Onconase)]]
* [[Rasburicase|Rasburicase (Elitek)]]
* [[Regorafenib|Regorafenib (Stivarga)]]
* [[Rituximab|Rituximab (Rituxan)]]
* [[Romidepsin|Romidepsin (Istodax)]]
* [[Ruxolitinib|Ruxolitinib (Jakafi)]]
* [[Sargramostim|Sargramostim (Leukine, Leukomax)]]
* [[Siltuximab|Siltuximab (Sylvant)]]
* [[Sipuleucel-T|Sipuleucel-T (Provenge)]]
* [[Sorafenib|Sorafenib (Nexavar)]]
* [[Streptozocin|Streptozocin (Zanosar)]]
* [[Sunitinib|Sunitinib (Sutent)]]
* [[Tamoxifen|Tamoxifen (Nolvadex)]]
* [[Tbo-filgrastim|Tbo-filgrastim (Granix)]]
* [[Temozolomide|Temozolomide (Temodar)]]
* [[Temsirolimus|Temsirolimus (Torisel)]]
* [[Teniposide|Teniposide (Vumon)]]
* [[Testolactone|Testolactone (Teslac)]]
* [[Thalidomide|Thalidomide (Thalomid)]]
* [[Thioguanine|Thioguanine (Tabloid)]]
* [[Thiotepa|Thiotepa (Tepadina)]]
* [[Tocilizumab|Tocilizumab (Actemra)]]
* [[Topotecan|Topotecan (Hycamtin)]]
* [[Toremifene|Toremifene (Fareston)]]
* [[Tositumomab|Tositumomab (Bexxar)]]
* [[Trabectedin|Trabectedin (Yondelis)]]
* [[Trametinib|Trametinib (Mekinist)]]
* [[Trastuzumab|Trastuzumab (Herceptin)]]
* [[Tretinoin|Tretinoin (Vesanoid)]]
* [[Trilostane|Trilostane (Modrenal)]]
* [[Triptorelin pamoate|Triptorelin pamoate (Trelstar)]]
* [[Valrubicin|Valrubicin (Valstar)]]
* [[Vandetanib|Vandetanib (Caprelsa)]]
* [[Vemurafenib|Vemurafenib (Zelboraf)]]
* [[Vinblastine|Vinblastine (Velban, Velsar)]]
* [[Vincristine|Vincristine (Oncovin, Vincasar)]]
* [[Vincristine liposome|Vincristine liposome (Marqibo)]]
* [[Vinflunine|Vinflunine (Javlor)]]
* [[Vinorelbine|Vinorelbine (Navelbine)]]
* [[Vismodegib|Vismodegib (Erivedge)]]
* [[Vorinostat|Vorinostat (Zolinza)]]
* [[Ziv-aflibercept|Ziv-aflibercept (Zaltrap)]]
* [[Zoledronic acid|Zoledronic Acid (Zometa)]]
}}


{{SIB}}
[[Category:Chemotherapeutic agents| ]]
[[Category:Chemotherapeutic agents| ]]
[[de:Zytostatikum]]
[[fr:Agent chimiothérapeutique]]
[[nl:Cytostaticum]]
[[pl:Leki cytostatyczne]]
{{WH}}
{{WS}}

Latest revision as of 04:08, 22 March 2015

Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]

Overview

This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).

Chemotherapeutic Agents by Category

Alkylating agents

Nitrogen mustards
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes

Antimetabolites

Folic acid analogs
Pyrimidine analogs
Purine analogs
Ribonucleotide reductase inhibitors

Natural products

Vinca alkaloids
Taxanes
Epipodophyllotoxins
Camptothecins
Antineoplastic antibiotics
Antineoplastic enzymes

Hormones and Antagonists

Adrenocortical suppressants
Glucocorticoids
Progestins
Estrogens
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
LHRH agonists
GnRH agonists
GnRH antagonists

Biologics

Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-6 inhibitors
Immunotherapy

Hematopoietic Growth Factors

Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors

Supportive Medications

Chemotherapy protective agents
Antiemetic agents
RANK ligand inhibitors
Calcium regulators

Miscellaneous

Mitotic inhibitors
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Orphan drugs

Chemotherapeutic Agents in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
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